Cardiomyopathy causes: Difference between revisions

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{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Arrhythmogenic right ventricular dysplasia]], [[arterial calcification of infancy]], [[Brugada syndrome]], cardiac transplant rejection, cardiomyopathy-diabetes-deafness complex, cardiomyopathy-hypogonadism-metabolic anomalies complex, cardiomyopathy-renal anomalies, cardiomyopathy with myopathy due to COX deficiency, [[chronic tachycardia]], [[coronary artery disease]], [[endomyocardial fibrosis]], [[eosinophilic endomyocardial disease]], facio-cardio-musculo-skeletal syndrome, [[giant cell myocarditis]], [[myocarditis]], [[hypertension]], [[prolonged QT syndrome]], [[Loeffler endocarditis]], [[Keshan disease]], obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay, [[Naxos disease]], x-linked dilated cardiomyopathy, x-linked fatal infantile cardiomyopathy, [[left ventricular noncompaction]]
 
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |  
[[Arrhythmogenic right ventricular dysplasia]],  
[[arterial calcification of infancy]],  
[[Brugada syndrome]],  
[[cardiac transplant rejection]],
[[cardiomyopathy with myopathy due to COX deficiency]],  
[[cardiomyopathy-diabetes-deafness complex]],  
[[cardiomyopathy-hypogonadism-metabolic anomalies complex]],  
[[cardiomyopathy-renal anomalies]],  
[[chronic tachycardia]],  
[[coronary artery disease]],  
[[endomyocardial fibrosis]],  
[[eosinophilic endomyocardial disease]],  
[[facio-cardio-musculo-skeletal syndrome]],  
[[giant cell myocarditis]],  
[[hypertension]],  
[[Keshan disease]],  
[[left ventricular noncompaction]],  
[[Loeffler endocarditis]],  
[[myocarditis]],
[[Naxos disease]],  
[[obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay]],  
[[prolonged QT syndrome]],  
[[x-linked dilated cardiomyopathy]],  
[[x-linked fatal infantile cardiomyopathy]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Chemical / poisoning'''
| '''Chemical / poisoning'''
|bgcolor="Beige"| [[Arsenic]], [[Cobalt]], Endothall, [[Ethanol]], [[Lead]], [[Thallium]]
|bgcolor="Beige"| [[Arsenic]], [[cobalt]], endothall, [[ethanol]], [[lead]], [[thallium]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"

Revision as of 16:53, 9 August 2013

Cardiomyopathy Microchapters

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Overview

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Differentiating Cardiomyopathy from other Diseases

Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There is a very wide range of factors that can cause cardiomyopathy, ranging from infectious causes, toxins, genetic causes and other disease processes.

Causes

Common Causes

Causes by Organ System

Cardiovascular

Arrhythmogenic right ventricular dysplasia, arterial calcification of infancy, Brugada syndrome, cardiac transplant rejection, cardiomyopathy with myopathy due to COX deficiency, cardiomyopathy-diabetes-deafness complex, cardiomyopathy-hypogonadism-metabolic anomalies complex, cardiomyopathy-renal anomalies, chronic tachycardia, coronary artery disease, endomyocardial fibrosis, eosinophilic endomyocardial disease, facio-cardio-musculo-skeletal syndrome, giant cell myocarditis, hypertension, Keshan disease, left ventricular noncompaction, Loeffler endocarditis, myocarditis, Naxos disease, obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay, prolonged QT syndrome, x-linked dilated cardiomyopathy, x-linked fatal infantile cardiomyopathy

Chemical / poisoning Arsenic, cobalt, endothall, ethanol, lead, thallium
Dermatologic Familial cutaneous collagenoma, Lentiginosis, Dermatomyositis
Drug Side Effect Aclarubicin, Anthracyclines, Bleomycin, Clozapine, Cyclophosphamide, Doxorubicin, Idarubicin, Mitoxantrone, Paracetamol, Peplomycin, Tacrolimus, Tricyclic anti-depressant abuse
Ear Nose Throat No underlying causes
Endocrine Acromegaly, Cushing's Disease, Diabetes Mellitus, Hyperparathyroidism, Hyperthyroidism, Hypothyroidism, Pheochromocytoma, Pituitary tumor (growth hormone secreting), Cardiomyopathy - diabetes - deafness, Cardiomyopathy -- hypogonadism -- metabolic anomalies complex, Obesity -- colitis -- hypothyroidism -- cardiac hypertrophy -- developmental delay, Carcinoid syndrome
Environmental Heatstroke, Hypothermia, Lightening strike
Gastroenterologic Hemochromatosis, Hepatitis, Obesity -- colitis -- hypothyroidism -- cardiac hypertrophy -- developmental delay complex, Whipple's Disease
Genetic Alpers Syndrome, Familial cardiomyopathy, Hutchinson-Gilford progeria syndrome, Noonan syndrome, Sarcoglycanopathy, X-linked - fatal infantile Cardiomyopathy, Friedrich's Ataxia, Brugada syndrome
Hematologic Cardiomyopathy -- spherocytosis
Iatrogenic No underlying causes
Infectious Disease

Bacteria: Beta-hemolytic streptococci, Borrelia burgdorferi, Brucella, Diptheria, Enterococci , Leptospirosis, Lyme Disease, Pertussis, Psittacosis, Q Fever, Rocky Mountain Spotted Fever, Staphylococcus, Syphilis, Tetanus, Tuberculosis, Typhoid Fever, Rheumatic Fever

Virus: Adenovirus, Arbovirus, Coxsackie virus A, Coxsackie virus B1-B5, Cytomegalovirus (CMV), ECHO virus (EnteroCytopathogenic Human Orphan viruses), Epstein-Barr Virus (EBV), Flavivirus, HIV, Influenza, Measles, Mumps,Oral candidiasis, Polio, Rabies, Varicella-zoster virus

Fungi: Aspergillosis, Blastomycosis, Coccidioidomycosis, Cryptococcosis, Histoplasmosis

Parasites: African Sleeping sickness, Amebiasis, Ascariasis, Chagas disease, Cysticercosis, Filariasis, Leishmaniasis, Loeffler endocarditis, Malaria, Sarcosporidiosis, Schistosomiasis, Toxoplasmosis, Trichinosis

Musculoskeletal / Ortho Dermatomyositis, Arthrogryposis due to muscular dystrophy, Duchenne muscular dystrophy, Emery-Dreifuss muscular dystrophy, Limb girdle muscular dystrophy, Mitochondrial myopathy, Muscular Dystrophy, Myotonic dystrophy, Recessive type Metaphyseal chondrodysplasia, Kearns-Sayre Syndrome, Cardiomyopathy with myopathy due to COX deficency, Facio-cardio-musculo-skeletal syndrome, Hand-Schuller-Christian Syndrome
Neurologic Friedrich's Ataxia, Kearns-Sayre Syndrome, Whipple's Disease, Alpers Syndrome, Hand-Schuller-Christian Syndrome, MELAS
Nutritional / Metabolic 3-methylglutaconic aciduria type 4, Beri-Beri (thiamine or vitamin B1), Carbohydrate deficient glycoprotein syndrome type 1a, Carnitine deficiency, Carnitine palmitoyltransferase 2 deficiency, Carnitine transporter deficiency, Coenzyme Q 10 (CoQ10) deficiency, Coenzyme Q cytochrome c reductase deficiency, Congenital disorder of glycosylation, Cytochrome C Oxidase deficiency, Fabry's Disease, Gangliosidosis, Gaucher's Disease, Glutaric acidemia type 2, Glycogen storage diseases, Gout, Hunter's Syndrome, Hurler's Syndrome, Keshan disease, Kwashiorkor, Malonic aciduria, MELAS, Neimann-Pick Disease, Niacin deficiency, Oxalosis, Porphyria, Refsum's disease, scurvy, Triosephosphate isomerase deficiency, Vitamin B deficiency, Vitamin D overdose , Hemochromatosis
Obstetric/Gynecologic Peripartum cardiomyopathy
Oncologic Angioma, Myxomas, Pituitary tumour (growth hormone secreting), Rhabdomyoma, Sarcoma, Leukemia, WAGR Syndrome, Carcinoid syndrome
Opthalmologic Hand-Schuller-Christian Syndrome, Microphthalmia, syndromic 7, Myotonic dystrophy, WAGR Syndrome
Overdose / Toxicity No underlying causes
Psychiatric Takotsubo cardiomyopathy
Pulmonary No underlying causes
Renal / Electrolyte Electrolyte imbalance, Hypocalcemia, Hypokalemia, Hypomagnesemia, Uremia, WAGR Syndrome, MELAS
Rheum / Immune / Allergy Polyarteritis nodosa, Rheumatoid Arthritis, Sarcoidosis, Scleroderma, Systemic Lupus Erythematosus, Kawasaki's Disease, Gout
Sexual No underlying causes
Trauma Trauma
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Cocaine abuse, Alcoholism, Amyloidosis, Electric shock, Idiopathic dilated cardiomyopathy, Immunoglobulinic amyloidosis, Irradiation, Mitochondrial trifunctional protein deficiency, Obesity, physically and physiologically stress induced (tako-tsubo syndrome or "broken heart syndrome"), Toxic mushrooms -- cyclopeptides

Causes in Alphabetical Order

Genetic Causes of Cardiomyopathy

Phenotype Inheritance Pattern Chromosomal Locus Gene Protein Skeletal Myopathy
Dilated cardiomyopathy X-linked Xp21 dystrophin Dystrophin Duchenne / Becker muscular dystrophy
X-linked Xq28 G4.5 Tafazzin Barth syndrome
Autosomal dominant 15q14 actin Actin Nemaline myopathy
2q35 desmin Desmin Desmin myopathy
5q33 δ-sarcoglycan δ-sarcoglycan Limb girdle muscular dystrophy 2F
1q32 Troponin T Troponin T
14q11 β-myosin heavy chain β-myosin heavy chain
15q2 α-tropomyosin α-tropomyosin Nemaline myopathy
Midna Mitochondrial respiratory chain Mitochondrial respiratory chain Mitochondrial myopathy
Dilated cardiomyopathy with conduction disease Autosomal dominant 1q21 lamin A/C Lamin A/C Emery-Dreifuss muscular dystrophy
Hypertrophic cardiomyopathy Autosomal dominant 14q11 β-myosin heavy chain β-myosin heavy chain
14q11 β-myosin heavy chain β-myosin heavy chain
1q32 Troponin T Troponin T
12q23 Troponin T Troponin T
15q2 α-tropomyosin α-tropomyosin Nemaline myopathy
11q11 myosin-binding protein C myosin-binding protein C
3p21 myosin essential light chain myosin essential light chain
3p21 myosin regulatory light chain myosin regulatory light chain
2p31 titin Titin
Hypertrophic cardiomyopathy with Wolf-Parkinson-White syndrome 7q3 AMPK AMPK
MIDINA Mitochondrial respiratory chain Mitochondrial respiratory chain Mitochondrial myopathy
Left ventricular noncompaction X-linked Xq28 G4.5 Tafazzin Barth syndrome
Autosomal dominant 18q12 α-dystrobrevin α-dystrobrevin Muscular dystrophy

Table from article *"The Failing Heart". Nature. June 15, 2007

References

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