Autoimmune hemolytic anemia MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]

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Overview

There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia, but MRI can be helpful in assessing for spleen size or iron overload.

MRI

There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia. However, MRI of the abdomen can be done to assess for other conditions related to autoimmune hemolytic anemia.

  • Assessment for spleen size: MRI of the abdomen can be done to assess for spleen size if there is concern about spleen enlargement. Spleen enlargement typically occurs in extravascular hemolysis. MRI is a more expensive diagnostic test than CT and should only be done if ultrasound or CT are contraindicated or nondiagnostic. For example, contraindications to CT scan include patients with known reaction to iodinated contrast, renal dysfunction, or concern about radiation exposure.
  • Assessment for iron overload: Cardiac or hepatic MRI can also be done to assess for iron overload from frequent packed red blood cell transfusions. The T2 STAR sequence can assess specifically for iron overload in the heart and liver.

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