Autoimmune hemolytic anemia MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]; Associate Editor(s)-in-Chief: Irfan Dotani

Overview

There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia, but MRI can be helpful in assessing for spleen size or iron overload.

MRI

There is no primary role for MRI in the evaluation of autoimmune hemolytic anemia. However, MRI of the abdomen can be done to assess for other conditions related to autoimmune hemolytic anemia.

  • Assessment for spleen size:
    • MRI of the abdomen can be done to assess for spleen size if there is concern about spleen enlargement.
    • Spleen enlargement typically occurs in extravascular hemolysis.
    • MRI is a more expensive diagnostic test than CT and should only be done if ultrasound or CT are contraindicated or nondiagnostic.
    • For example, contraindications to CT scan include patients with known reaction to iodinated contrast, renal dysfunction, or concern about radiation exposure.[1][2]
  • Assessment for iron overload:

References

  1. Linguraru MG, Sandberg JK, Jones EC, Summers RM (2013). "Assessing splenomegaly: automated volumetric analysis of the spleen". Acad Radiol. 20 (6): 675–84. doi:10.1016/j.acra.2013.01.011. PMC 3945039. PMID 23535191.
  2. Palas J, Matos AP, Ramalho M (2013). "The spleen revisited: an overview on magnetic resonance imaging". Radiol Res Pract. 2013: 219297. doi:10.1155/2013/219297. PMC 3859258. PMID 24377046.
  3. Wood JC (2014). "Use of magnetic resonance imaging to monitor iron overload". Hematol Oncol Clin North Am. 28 (4): 747–64, vii. doi:10.1016/j.hoc.2014.04.002. PMC 4115249. PMID 25064711.
  4. Tziomalos K, Perifanis V (2010). "Liver iron content determination by magnetic resonance imaging". World J Gastroenterol. 16 (13): 1587–97. PMC 2848367. PMID 20355237.

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