Autoimmune hemolytic anemia history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2], Irfan Dotani

Overview

Patients with autoimmune hemolytic anemia have a gradual onset of fatigue and can develop shortness of breath and decreased exercise tolerance. The symptoms of autoimmune hemolytic anemia depend on the severity of the disease.

History and Symptoms

History

• Patients will usually have report a gradual onset of fatigue.

Symptoms

• Patients may be asymptomatic if the anemia is mild.

Common Symptoms

Common symptoms of autoimmune hemolytic anemia include:

• Fatigue (feeling weak or tired more often than usual)
• Decreased exercise tolerance
• Headaches
• Problems concentrating or thinking

Symptoms of severe anemia may include:

• Blue color to the sclera
• Brittle nails
• Light-headedness upon standing
• Pale skin color (pallor)
• Shortness of breath
• Sore tongue
• Palpitations
• Angina
• Abdominal pain (from splenomegaly)