Autoimmune hemolytic anemia diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Diagnosis of autoimmune hemolytic anemia is based on laboratory results. The best way to make a diagnosis is to start with a less costly CBC followed by confirmatory coombs test to define type of autoimmune hemolysis.

Diagnotic study of choice for autoimmune hemolytic anemia

  • Diagnosis of autoimmune hemolytic anemia is based on laboratory results. [1]
  • The best way to make a diagnosis is to start with a less costly CBC followed by confirmatory coombs test to define type of autoimmune hemolysis.
  • By definition, autoimmune hemolytic anemia is characterized by anemia.[2]
  • Seeing schistocytes in peripheral blood smear is a sensitive but non-specific test for diagnosis of autoimmune hemolytic anemia.
  • Coombs test can narrow down our diagnosis in autoimmune hemolytic anemia.

Refrences

  1. Biswas S. Chandrashekhar P. Varghese M (2007). "Coomb's Positive Hemolytic Anemia Due To Insect Bite". Oman Med J. 22 (3): 62–3. PMC 3294156. PMID 22400097.
  2. Berentsen S, Sundic T (2015). "Red blood cell destruction in autoimmune hemolytic anemia: role of complement and potential new targets for therapy". Biomed Res Int. 2015: 363278. doi:10.1155/2015/363278. PMC 4326213. PMID 25705656.