AM-905

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AM-905
File:AM-905.png
Identifiers
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC23H34O3
Molar mass358.513 g/mol
3D model (JSmol)

AM-905 is an analgesic drug which is a cannabinoid agonist with a conformationally restricted side chain. It is a potent and reasonably selective agonist for the CB1 cannabinoid receptor, with a Ki of 1.2nM at CB1 vs 5.3nM at CB2.[1]

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References

  1. Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A. Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols. Journal of Medicinal Chemistry. 1998 Mar 26;41(7):1195-200. PMID 9544219

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