ST elevation myocardial infarction coronary artery bypass grafting

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

Jump to: navigation, search
Myocardial infarction
Classification and external resources
Diagram of a myocardial infarction (2) of the tip of the anterior wall of the heart (an apical infarct) after occlusion (1) of a branch of the left coronary artery (LCA, right coronary artery = RCA).
ICD-10 I21.-I22.
ICD-9 410
DiseasesDB 8664
MedlinePlus 000195
eMedicine med/1567  emerg/327 ped/2520

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753

Associate Editors-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Cardiology Network

Discuss ST elevation myocardial infarction coronary artery bypass grafting further in the WikiDoc Cardiology Network
Adult Congenital
Biomarkers
Cardiac Rehabilitation
Congestive Heart Failure
CT Angiography
Echocardiography
Electrophysiology
Cardiology General
Genetics
Health Economics
Hypertension
Interventional Cardiology
MRI
Nuclear Cardiology
Peripheral Arterial Disease
Prevention
Public Policy
Pulmonary Embolism
Stable Angina
Valvular Heart Disease
Vascular Medicine

Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Coronary Artery Bypass Surgery

Coronary artery bypass surgery during mobilization (freeing) of the right coronary artery from its surrounding tissue, adipose tissue (yellow).  The tube visible at the bottom is the aortic cannula (returns blood from the HLM).  The tube above it (obscured by the surgeon on the right) is the venous cannula (receives blood from the body).  The patient's heart is stopped and the aorta is cross-clamped.  The patient's head (not seen) is at the bottom.
Coronary artery bypass surgery during mobilization (freeing) of the right coronary artery from its surrounding tissue, adipose tissue (yellow). The tube visible at the bottom is the aortic cannula (returns blood from the HLM). The tube above it (obscured by the surgeon on the right) is the venous cannula (receives blood from the body). The patient's heart is stopped and the aorta is cross-clamped. The patient's head (not seen) is at the bottom.

Despite the guidelines, emergency bypass surgery for the treatment of an acute myocardial infarction (MI) is less common then PCI or medical management. In an analysis of patients in the U.S. National Registry of Myocardial Infarction (NRMI) from January 1995 to May 2004, the percentage of patients with cardiogenic shock treated with primary PCI rose from 27.4% to 54.4%, while the increase in CABG treatment was only from 2.1% to 3.2%.[1]

Emergency coronary artery bypass graft surgery (CABG) is usually undertaken to simultaneously treat a mechanical complication, such as a ruptured papillary muscle, or a ventricular septal defect, with ensueing cardiogenic shock.[2] In uncomplicated MI, the mortality rate can be high when the surgery is performed immediately following the infarction.[3] If this option is entertained, the patient should be stabilized prior to surgery, with supportive interventions such as the use of an intra-aortic balloon pump.[4] In patients developing cardiogenic shock after a myocardial infarction, both PCI and CABG are satisfactory treatment options, with similar survival rates.[5][6]

Coronary artery bypass surgery involves an artery or vein from the patient being implanted to bypass narrowings or occlusions on the coronary arteries. Several arteries and veins can be used, however internal mammary artery grafts have demonstrated significantly better long-term patency rates than great saphenous vein grafts.[7] In patients with two or more coronary arteries affected, bypass surgery is associated with higher long-term survival rates compared to percutaneous interventions.[8] In patients with single vessel disease, surgery is comparably safe and effective, and may be a treatment option in selected cases.[9] Bypass surgery has higher costs initially, but becomes cost-effective in the long term.[10] A surgical bypass graft is more invasive initially but bears less risk of recurrent procedures (but these may be again minimally invasive).

ACC / AHA Guidelines (DO NOT EDIT)[11]

Class I

1. Emergency or urgent CABG in patients with STEMI should be undertaken in the following circumstances:

a. Failed PCI with persistent pain or hemodynamic instability in patients with coronary anatomy suitable for surgery. (Level of Evidence: B)
b. Persistent or recurrent ischemia refractory to medical therapy in patients who have coronary anatomy suitable for surgery, have a significant area of myocardium at risk, and are not candidates for PCI or fibrinolytic therapy. (Level of Evidence: B)
c. At the time of surgical repair of post infarction ventricular septal rupture (VSR) or mitral valve insufficiency. (Level of Evidence: B)
d. Cardiogenic shock in patients less than 75 years old with ST elevation or LBBB or posterior MI who develop shock within 36 hours of STEMI, have severe multivessel or left main disease, and are suitable for revascularization that can be performed within 18 hours of shock, unless further support is futile because of the patient’s wishes or contraindications/unsuitability for further invasive care. (Level of Evidence: A)
e. Life-threatening ventricular arrhythmias in the presence of greater than or equal to 50% left main stenosis and/or triple-vessel disease. (Level of Evidence: B)

Class IIa

1. Emergency CABG can be useful as the primary reperfusion strategy in patients who have suitable anatomy and who are not candidates for fibrinolysis or PCI and who are in the early hours (6 to 12 hours) of an evolving STEMI, especially if severe multivessel or left main disease is present. (Level of Evidence: B)

2. Emergency CABG can be effective in selected patients 75 years or older with ST elevation, LBBB, or posterior MI who develop shock within 36 hours of STEMI, have severe triple-vessel or left main disease, and are suitable for revascularization that can be performed within 18 hours of shock. Patients with good prior functional status who are suitable for revascularization and agree to invasive care may be selected for such an invasive strategy. (Level of Evidence: B)

Class III

1. Emergency CABG should not be performed in patients with persistent angina and a small area of risk who are hemodynamically stable. (Level of Evidence: C)

2. Emergency CABG should not be performed in patients with successful epicardial reperfusion but unsuccessful microvascular reperfusion. (Level of Evidence: C)

See also

Sources

  • The 2004 ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction [12]
  • The 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients with ST-Elevation Myocardial Infarction [11]

References

  1. Babaev A, Frederick PD, Pasta DJ, Every N, Sichrovsky T, Hochman JS (July 2005). "Trends in management and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock". JAMA 294 (4): 448–54. doi:10.1001/jama.294.4.448. PMID 16046651.
  2. Townsend, Courtney M.; Beauchamp D.R., Evers M.B., Mattox K.L. (2004). Sabiston Textbook of Surgery - The Biological Basis of Modern Surgical Practice. Philadelphia, Pennsylvania: Elsevier Saunders, 1871. ISBN 0-7216-0409-9. 
  3. Kaul TK, Fields BL, Riggins SL, Dacumos GC, Wyatt DA, Jones CR (May 1995). "Coronary artery bypass grafting within 30 days of an acute myocardial infarction". Ann. Thorac. Surg. 59 (5): 1169–76. PMID 7733715.
  4. Creswell LL, Moulton MJ, Cox JL, Rosenbloom M (July 1995). "Revascularization after acute myocardial infarction". Ann. Thorac. Surg. 60 (1): 19–26. PMID 7598589.
  5. White HD, Assmann SF, Sanborn TA, et al (September 2005). "Comparison of percutaneous coronary intervention and coronary artery bypass grafting after acute myocardial infarction complicated by cardiogenic shock: results from the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) trial". Circulation 112 (13): 1992–2001. doi:10.1161/CIRCULATIONAHA.105.540948. PMID 16186436.
  6. Hochman JS, Sleeper LA, Webb JG, et al (June 2006). "Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction". JAMA 295 (21): 2511–5. doi:10.1001/jama.295.21.2511. PMID 16757723.
  7. Raja SG, Haider Z, Ahmad M, Zaman H (December 2004). "Saphenous vein grafts: to use or not to use?". Heart Lung Circ 13 (4): 403–9. doi:10.1016/j.hlc.2004.04.004. PMID 16352226.
  8. Hannan EL, Racz MJ, Walford G, et al (May 2005). "Long-term outcomes of coronary-artery bypass grafting versus stent implantation". N. Engl. J. Med. 352 (21): 2174–83. doi:10.1056/NEJMoa040316. PMID 15917382.
  9. Bourassa MG (July 2000). "Clinical trials of coronary revascularization: coronary angioplasty vs. coronary bypass grafting". Curr. Opin. Cardiol. 15 (4): 281–6. PMID 11139092.
  10. Hlatky MA, Boothroyd DB, Melsop KA, et al (October 2004). "Medical costs and quality of life 10 to 12 years after randomization to angioplasty or bypass surgery for multivessel coronary artery disease". Circulation 110 (14): 1960–6. doi:10.1161/01.CIR.0000143379.26342.5C. PMID 15451795.
  11. 11.0 11.1 Antman EM, Hand M, Armstrong PW, et al (January 2008). "2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration With the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf of the 2004 Writing Committee". Circulation 117 (2): 296–329. doi:10.1161/CIRCULATIONAHA.107.188209. PMID 18071078.
  12. Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, Hochman JS, Krumholz HM, Kushner FG, Lamas GA, Mullany CJ, Ornato JP, Pearle DL, Sloan MA, Smith SC, Alpert JS, Anderson JL, Faxon DP, Fuster V, Gibbons RJ, Gregoratos G, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK (August 2004). "ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction)". Circulation 110 (9): e82–292. PMID 15339869.

External links



WikiDoc Help Menu

Quick Start..

Editing basics

Advanced editing

Communicating your edits

Help Videos You Can Watch

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

Personal tools