Potassium-sparing diuretic

(Redirected from Potassium-sparing)
Jump to navigation Jump to search

WikiDoc Resources for Potassium-sparing diuretic

Articles

Most recent articles on Potassium-sparing diuretic

Most cited articles on Potassium-sparing diuretic

Review articles on Potassium-sparing diuretic

Articles on Potassium-sparing diuretic in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Potassium-sparing diuretic

Images of Potassium-sparing diuretic

Photos of Potassium-sparing diuretic

Podcasts & MP3s on Potassium-sparing diuretic

Videos on Potassium-sparing diuretic

Evidence Based Medicine

Cochrane Collaboration on Potassium-sparing diuretic

Bandolier on Potassium-sparing diuretic

TRIP on Potassium-sparing diuretic

Clinical Trials

Ongoing Trials on Potassium-sparing diuretic at Clinical Trials.gov

Trial results on Potassium-sparing diuretic

Clinical Trials on Potassium-sparing diuretic at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Potassium-sparing diuretic

NICE Guidance on Potassium-sparing diuretic

NHS PRODIGY Guidance

FDA on Potassium-sparing diuretic

CDC on Potassium-sparing diuretic

Books

Books on Potassium-sparing diuretic

News

Potassium-sparing diuretic in the news

Be alerted to news on Potassium-sparing diuretic

News trends on Potassium-sparing diuretic

Commentary

Blogs on Potassium-sparing diuretic

Definitions

Definitions of Potassium-sparing diuretic

Patient Resources / Community

Patient resources on Potassium-sparing diuretic

Discussion groups on Potassium-sparing diuretic

Patient Handouts on Potassium-sparing diuretic

Directions to Hospitals Treating Potassium-sparing diuretic

Risk calculators and risk factors for Potassium-sparing diuretic

Healthcare Provider Resources

Symptoms of Potassium-sparing diuretic

Causes & Risk Factors for Potassium-sparing diuretic

Diagnostic studies for Potassium-sparing diuretic

Treatment of Potassium-sparing diuretic

Continuing Medical Education (CME)

CME Programs on Potassium-sparing diuretic

International

Potassium-sparing diuretic en Espanol

Potassium-sparing diuretic en Francais

Business

Potassium-sparing diuretic in the Marketplace

Patents on Potassium-sparing diuretic

Experimental / Informatics

List of terms related to Potassium-sparing diuretic

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Potassium-sparing diuretic refers to diuretic drugs that do not promote the secretion of potassium into the urine. They are used as adjunctive therapy, together with other drugs, in the treatment of hypertension and management of congestive heart failure.

Mechanism of action

Potassium-sparing diuretics decrease sodium reabsorption at collecting tubules, inducing diuresis; decrease activity of aldosterone at collecting tubules.

Indications

Potassium-sparing diuretics are generally used in combination with other diuretic drugs (e.g. loop diuretics) that would otherwise tend to lower the potassium levels to potentially dangerous low levels (hypokalemia). The combination therefore helps maintain a normal reference range for potassium.

Side effects

On their own this group of drugs may raise potassium levels beyond the normal range, termed hyperkalemia, which risks potentially fatal arrhythmias.

Chemical structure

Potassium-sparing diuretics do not share any obvious chemical similarities, except for the steroid-structure of the aldosterone antagonists. Those in clinical use include:

See also

External links

References

  • Block JH, Beale JM. "Organic Medicinal and Pharmaceutical Chemistry" 11th edition. Lippincott Williams & Wilkins. 2004.


Template:SIB

Template:WikiDoc Sources