Parkinson's disease other diagnostic studies
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Overview
Response to dopaminergic therapy: One of the useful methods in diagnosing PD is patient response to dopaminergic therapy. Levodopa and apomorphine challenge tests in proven to be useful in distinguishing PD from other parkinsonian syndromes.
Autonomic testing: Autonomic testing including cardiac sympathetic denervation, urodynamic testing, anal or urethral EMG, sympathetic skin responses, quantitative sudomotor axon reflex test, tilt table test and heart rate variability during forced respirations are also useful in diagnosing PD.
Olfactory testing: Olfactory testing is a useful test since olfactory dysfunction in common in PD but not in other parkinsonian syndromes and essential tremor.
Other diagnostic studies
Other diagnostic studies for Parkinson include:
- Response to dopaminergic therapy: One of the useful methods in diagnosing PD is patient response to dopaminergic therapy. Levodopa and apomorphine challenge tests in proven to be useful in distinguishing PD from other parkinsonian syndromes.[1]
- Autonomic testing: Autonomic testing including cardiac sympathetic denervation, urodynamic testing, anal or urethral EMG, sympathetic skin responses, quantitative sudomotor axon reflex test, tilt table test and heart rate variability during forced respirations are also useful in diagnosing PD.[1][2]
- Olfactory testing: Olfactory testing is a useful test since olfactory dysfunction in common in PD but not in other parkinsonian syndromes and essential tremor.[3]
References
- ↑ 1.0 1.1 Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ (April 2006). "Practice Parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology". Neurology. 66 (7): 968–75. doi:10.1212/01.wnl.0000215437.80053.d0. PMID 16606907.
- ↑ Orimo S, Suzuki M, Inaba A, Mizusawa H (June 2012). "123I-MIBG myocardial scintigraphy for differentiating Parkinson's disease from other neurodegenerative parkinsonism: a systematic review and meta-analysis". Parkinsonism Relat. Disord. 18 (5): 494–500. doi:10.1016/j.parkreldis.2012.01.009. PMID 22321865.
- ↑ Katzenschlager R, Lees AJ (August 2004). "Olfaction and Parkinson's syndromes: its role in differential diagnosis". Curr. Opin. Neurol. 17 (4): 417–23. PMID 15247536.