IgA nephropathy causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2];Olufunmilola Olubukola M.D.[3]

Overview

The cause of primary IgA nephropathy is unknown. Additionally, there are no known infectious or environmental associated factors. However, IgA nephropathy is associated with some genetic mutations and familial clustering as a postulated cause of primary IgAN. Liver cirrhosis, celiac disease, HIV infection are the most common etiologies associated with glomerular IgA deposits and thus secondary IgA nephropathy.

Causes

Primary IgA Nephropathy

Secondary IgA Nephropathy

The most common etiologies associated with glomerular IgA deposits and thus secondary IgA nephropathy include:

References

  1. Hsu SI, Ramirez SB, Winn MP, Bonventre JV, Owen WF (2000). "Evidence for genetic factors in the development and progression of IgA nephropathy". Kidney Int. 57 (5): 1818–35. doi:10.1046/j.1523-1755.2000.00032.x. PMID 10792601.
  2. 2.0 2.1 2.2 Radhakrishnan J, Cattran DC (2012). "The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines--application to the individual patient". Kidney Int. 82 (8): 840–56. doi:10.1038/ki.2012.280. PMID 22895519.

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