Epoxyeicosatrienoic acid

Jump to: navigation, search

WikiDoc Resources for Epoxyeicosatrienoic acid

Articles

Most recent articles on Epoxyeicosatrienoic acid

Most cited articles on Epoxyeicosatrienoic acid

Review articles on Epoxyeicosatrienoic acid

Articles on Epoxyeicosatrienoic acid in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Epoxyeicosatrienoic acid

Images of Epoxyeicosatrienoic acid

Photos of Epoxyeicosatrienoic acid

Podcasts & MP3s on Epoxyeicosatrienoic acid

Videos on Epoxyeicosatrienoic acid

Evidence Based Medicine

Cochrane Collaboration on Epoxyeicosatrienoic acid

Bandolier on Epoxyeicosatrienoic acid

TRIP on Epoxyeicosatrienoic acid

Clinical Trials

Ongoing Trials on Epoxyeicosatrienoic acid at Clinical Trials.gov

Trial results on Epoxyeicosatrienoic acid

Clinical Trials on Epoxyeicosatrienoic acid at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Epoxyeicosatrienoic acid

NICE Guidance on Epoxyeicosatrienoic acid

NHS PRODIGY Guidance

FDA on Epoxyeicosatrienoic acid

CDC on Epoxyeicosatrienoic acid

Books

Books on Epoxyeicosatrienoic acid

News

Epoxyeicosatrienoic acid in the news

Be alerted to news on Epoxyeicosatrienoic acid

News trends on Epoxyeicosatrienoic acid

Commentary

Blogs on Epoxyeicosatrienoic acid

Definitions

Definitions of Epoxyeicosatrienoic acid

Patient Resources / Community

Patient resources on Epoxyeicosatrienoic acid

Discussion groups on Epoxyeicosatrienoic acid

Patient Handouts on Epoxyeicosatrienoic acid

Directions to Hospitals Treating Epoxyeicosatrienoic acid

Risk calculators and risk factors for Epoxyeicosatrienoic acid

Healthcare Provider Resources

Symptoms of Epoxyeicosatrienoic acid

Causes & Risk Factors for Epoxyeicosatrienoic acid

Diagnostic studies for Epoxyeicosatrienoic acid

Treatment of Epoxyeicosatrienoic acid

Continuing Medical Education (CME)

CME Programs on Epoxyeicosatrienoic acid

International

Epoxyeicosatrienoic acid en Espanol

Epoxyeicosatrienoic acid en Francais

Business

Epoxyeicosatrienoic acid in the Marketplace

Patents on Epoxyeicosatrienoic acid

Experimental / Informatics

List of terms related to Epoxyeicosatrienoic acid


Chemical structure of 14,15-epoxyeicosatrienoic acid.

The Epoxyeicosatrienoic acids or EETs are signaling molecules formed by the action of Cytochrome P450 epoxygenase on 20-carbon essential fatty acids, such as arachidonic acid. These nonclassic eicosanoids act as short-range hormones, (i.e. they are autocrine and paracrine mediators) of the cardiovascular system and kidney. They produce vasorelaxation as well as anti-inflammatory and pro-fibrinolytic effects.[1]

Biological effects

EETs are cardioprotective after ischemic heart attack and reperfusion.[2] They act in the corpus cavernosum to maintain penile erection.[3] Specific epoxidation of EET sites produces endogenous PPARα agonists.[4]

References

  1. ^ Nithipatikom K, Moore JM, Isbell MA, Falck JR, Gross GJ. "Epoxyeicosatrienoic acids (EETs) in cardioprotection: Ischemic versus reperfusion injury". Am J Physiol Heart Circ Physiol. date=2006 Feb 10. Retrieved 2006-03-11.
  2. ^ Jin L, Foss CE, Zhao X, Mills TM, Wang MH, McCluskey LP, Yaddanapud GS, Falck JR, Imig JD, Webb RC. (2006 Jan 13.). "Cytochrome P450 epoxygenases provide a novel mechanism for penile erection". FASEB J. 2006 Mar;20(3):539-41. Retrieved 2006-03-11. Check date values in: |date= (help)PubMed cite.
  3. ^ Spector AA,Fang X, Snyder GD, Weintraub NL (2004). "Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function". Prog Lipid Res. 43 (1): 55–90. PMID 14636671. Unknown parameter |month= ignored (help)
  4. ^ Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL (2007). "Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha". Drug Metab Dispos. 37 (7): 1126–1134. PMID 17431031. Unknown parameter |month= ignored (help)




Linked-in.jpg