Tumor lysis syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]

Overview

Symptoms of tumor lysis syndrome include nausea, vomiting, diarrhea, oliguria, confusion, delirium, and seizure.

History and Symptoms

History

Patients with tumor lysis syndrome may have a positive history of:[1]

  • Chemotherapy
  • Renal dysfunctiom
  • malignancy

Common Symptoms

Symptoms of tumor lysis syndrome include:[1][2]

Electrolytes disturbance Symptoms

Hyperphosphatemia

Hypocalcemia

Hyperkalemia

Hyperuricemia

Less Common Symptoms

  • Abdominal pain
  • Abdominal distention
  • Paralysis
  • Syncope
  • Altered mental status

References

  1. 1.0 1.1 Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/diagnosis-and-treatment/managing-side-effects/tumour-lysis-syndrome/?region=ab#symptoms
  2. Cairo MS, Bishop M (2004). "Tumour lysis syndrome: new therapeutic strategies and classification". Br J Haematol. 127 (1): 3–11. doi:10.1111/j.1365-2141.2004.05094.x. PMID 15384972.

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