Toxic multinodular goiter other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • There are no other diagnostic studies associated with [disease name].
  • [Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
  • Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

Fine needle aspiration

The most important diagnostic test to differentiate thyroid nodules from each other is fine needle aspiration (FNA). As FNA is considered as an aggressive procedure, the American Thyroid Association developed the following criteria for FNA indication:

  • Nodules ≥ 1 cm with intermediate or high suspicion US pattern
  • Nodules ≥ 1.5 cm with low suspicion US pattern
  • Nodules ≥ 2 cm with very low suspicion US pattern (e.g., spongiform). Observation an alternate option
  • For nodules that do not meet the above criteria, FNA is not required, including nodules < 1 cm (with some exceptions) and purely cystic nodules 26462967
  • Criteria for US-guided FNA:
    • A higher likelihood of either a nondiagnostic cytology (>25–50% cystic component)
    • A higher likelihood of sampling error
      • Difficult to palpate nodules
      • Posteriorly located nodules

FNA biopsy is sensitive and specific in the diagnosis of childhood thyroid nodules. [1][2]

References

  1. Chang SH, Joo M, Kim H (2006). "Fine needle aspiration biopsy of thyroid nodules in children and adolescents". J. Korean Med. Sci. 21 (3): 469–73. doi:10.3346/jkms.2006.21.3.469. PMC 2729953. PMID 16778391.
  2. Hung W (1999). "Solitary thyroid nodules in 93 children and adolescents. a 35-years experience". Horm. Res. 52 (1): 15–8. doi:23426 Check |doi= value (help). PMID 10640894.

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