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{{SK}} Plummer's disease; toxic nodular goiter.
{{SK}} Plummer's disease; toxic nodular goiter.
== Overview ==


'''Toxic multinodular goitre''' (also known as '''toxic nodular goitre''', '''toxic nodular struma''') is a form of [[hyperthyroidism]] - where there is excess production of [[thyroid hormones]].
==[[Toxic multinodular goiter overview|Overview]]==


It is the second most common cause of [[hyperthyroidism]] after [[Graves disease]].
==[[Toxic multinodular goiter historical perspective|Historical Perspective]]==


==Symptoms==
==[[Toxic multinodular goiter classification|Classification]]==
Symptoms of toxic multinodular goitre are similar to that of [[hyperthyroidism]], including:
* heat intolerance
* [[hyperkinesis]]
* [[tremor]]
* irritability
* [[weight loss]]
* [[increased appetite]]
* [[goitre]] (swelling of the thyroid gland)
* [[tachycardia]] (high heart rate - above 180 bpm at rest)


==Related eponym==
==[[Toxic multinodular goiter pathophysiology|Pathophysiology]]==
'''Plummer's disease''' is named after an American [[physician]] [[Henry Stanley Plummer]] but refers to a '''single toxic nodule''' (adenoma) which may present with the background of a suppressed multinodular goitre.<ref>{{WhoNamedIt2|synd|1094|Plummer's disease}} eponymously named after {{WhoNamedIt|doctor|1074|Henry Stanley Plummer}}</ref>


==Footnotes==
==[[Toxic multinodular goiter causes|Causes]]==
<references/>
 
==[[Toxic multinodular goiter differential diagnosis|Differentiating Toxic multinodular goiter from other Diseases]]==
 
==[[Toxic multinodular goiter epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Toxic multinodular goiter risk factors|Risk Factors]]==
 
==[[Toxic multinodular goiter screening|Screening]]==
 
==[[Toxic multinodular goiter natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
 
==Diagnosis==
 
[[Toxic multinodular goiter history and symptoms|History and Symptoms]] | [[Toxic multinodular goiter physical examination|Physical Examination]] | [[Toxic multinodular goiter laboratory findings|Laboratory Findings]] | [[Toxic multinodular goiter electrocardiogram|Electrocardiogram]] | [[Toxic multinodular goiter x ray|X Ray]] | [[Toxic multinodular goiter CT|CT]] | [[Toxic multinodular goiter MRI|MRI]] | [[Toxic multinodular goiter echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Toxic multinodular goiter other imaging findings|Other Imaging Findings]] | [[Toxic multinodular goiter other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
 
[[Toxic multinodular goiter medical therapy|Medical Therapy]] | [[Toxic multinodular goiter surgery|Surgery]] | [[Toxic multinodular goiter prevention|Prevention]] | [[Toxic multinodular goiter cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Toxic multinodular goiter future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
 
[[Toxic multinodular goiter case study one|Case #1]]


==External links==
==External links==
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* [http://www.thyroidimaging.com/surg_gozimm2.htm Photo of goitre]
* [http://www.thyroidimaging.com/surg_gozimm2.htm Photo of goitre]


== Acknowledgements ==
[[pt:Doença de Plummer]]
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.


[[pt:Doença de Plummer]]
{{WH}}
{{WH}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}

Revision as of 14:22, 20 September 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Plummer's disease; toxic nodular goiter.

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Toxic multinodular goiter from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

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Medical Therapy | Surgery | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

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Case #1

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