Testicular receptor 4

Nuclear receptor subfamily 2, group C, member 2
Identifiers
Symbols	NR2C2 ; TAK1; TR2R1; TR4; hTAK1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2475
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NR2C2 206038 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Testicular receptor 4 is a member of the nuclear receptor family of transcription factors and is encoded by the NR2C2 gene (nuclear receptor subfamily 2, group C, member 2).

See also

• Testicular receptor

Further reading

• Hirose T, Fujimoto W, Tamaai T; et al. (1995). "TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily". Mol. Endocrinol. 8 (12): 1667–80. PMID 7708055.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chang C, Da Silva SL, Ideta R; et al. (1994). "Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily". Proc. Natl. Acad. Sci. U.S.A. 91 (13): 6040–4. PMID 8016112.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yoshikawa T, DuPont BR, Leach RJ, Detera-Wadleigh SD (1996). "New variants of the human and rat nuclear hormone receptor, TR4: expression and chromosomal localization of the human gene". Genomics. 35 (2): 361–6. doi:10.1006/geno.1996.0368. PMID 8661150.CS1 maint: Multiple names: authors list (link)
• Young WJ, Smith SM, Chang C (1997). "Induction of the intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRalpha) gene by the TR4 orphan receptor. A member of steroid receptor superfamily". J. Biol. Chem. 272 (5): 3109–16. PMID 9006963.CS1 maint: Multiple names: authors list (link)
• Lee CH, Chinpaisal C, Wei LN (1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4". J. Biol. Chem. 273 (39): 25209–15. PMID 9737983.CS1 maint: Multiple names: authors list (link)
• Lee YF, Shyr CR, Thin TH; et al. (2000). "Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily". Proc. Natl. Acad. Sci. U.S.A. 96 (26): 14724–9. PMID 10611280.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang X, Yeh S, Wu G; et al. (2001). "Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells". J. Biol. Chem. 276 (44): 40417–23. doi:10.1074/jbc.M104765200. PMID 11509567.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yeung KC, Rose DW, Dhillon AS; et al. (2001). "Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation". Mol. Cell. Biol. 21 (21): 7207–17. doi:10.1128/MCB.21.21.7207-7217.2001. PMID 11585904.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shyr CR, Hu YC, Kim E, Chang C (2002). "Modulation of estrogen receptor-mediated transactivation by orphan receptor TR4 in MCF-7 cells". J. Biol. Chem. 277 (17): 14622–8. doi:10.1074/jbc.M110051200. PMID 11844790.CS1 maint: Multiple names: authors list (link)
• Tanabe O, Katsuoka F, Campbell AD; et al. (2002). "An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer". EMBO J. 21 (13): 3434–42. doi:10.1093/emboj/cdf340. PMID 12093744.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yang Y, Wang X, Dong T; et al. (2003). "Identification of a novel testicular orphan receptor-4 (TR4)-associated protein as repressor for the selective suppression of TR4-mediated transactivation". J. Biol. Chem. 278 (9): 7709–17. doi:10.1074/jbc.M207116200. PMID 12486131.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin WJ, Li J, Lee YF; et al. (2003). "Suppression of hepatitis B virus core promoter by the nuclear orphan receptor TR4". J. Biol. Chem. 278 (11): 9353–60. doi:10.1074/jbc.M205944200. PMID 12522137.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takaesu G, Surabhi RM, Park KJ; et al. (2003). "TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway". J. Mol. Biol. 326 (1): 105–15. PMID 12547194.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Inui S, Lee YF, Chang E; et al. (2003). "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". J. Dermatol. Sci. 31 (1): 65–71. PMID 12615366.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ishitani T, Takaesu G, Ninomiya-Tsuji J; et al. (2004). "Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling". EMBO J. 22 (23): 6277–88. doi:10.1093/emboj/cdg605. PMID 14633987.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cheung PC, Nebreda AR, Cohen P (2004). "TAB3, a new binding partner of the protein kinase TAK1". Biochem. J. 378 (Pt 1): 27–34. doi:10.1042/BJ20031794. PMID 14670075.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bouwmeester T, Bauch A, Ruffner H; et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)