Testicular receptor 2

Nuclear receptor subfamily 2, group C, member 1
Identifiers
Symbols	NR2C1 ; TR2; TR2-11
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55731
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NR2C1 210530 s at tn.png
File:PBB GE NR2C1 210531 at tn.png
File:PBB GE NR2C1 204791 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

The testicular receptor 2 (TR2) is a member of the nuclear receptor family of transcription factors. TR2 is encoded by the NR2C1 gene (nuclear receptor subfamily 2, group C, member 1).

See also

• Testicular receptor

Further reading

• Chang C, Kokontis J, Acakpo-Satchivi L; et al. (1990). "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains". Biochem. Biophys. Res. Commun. 165 (2): 735–41. PMID 2597158.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chang C, Kokontis J (1988). "Identification of a new member of the steroid receptor super-family by cloning and sequence analysis". Biochem. Biophys. Res. Commun. 155 (2): 971–7. PMID 3421977.
• Lin DL, Wu SQ, Chang C (1998). "The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily". Endocrine. 8 (2): 123–34. PMID 9704569.CS1 maint: Multiple names: authors list (link)
• Lee CH, Chinpaisal C, Wei LN (1998). "A novel nuclear receptor heterodimerization pathway mediated by orphan receptors TR2 and TR4". J. Biol. Chem. 273 (39): 25209–15. PMID 9737983.CS1 maint: Multiple names: authors list (link)
• Lee CH, Chinpaisal C, Wei LN (1998). "Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor TR2". Mol. Cell. Biol. 18 (11): 6745–55. PMID 9774688.CS1 maint: Multiple names: authors list (link)
• Yu Z, Lee CH, Chinpaisal C, Wei LN (1999). "A constitutive nuclear localization signal from the second zinc-finger of orphan nuclear receptor TR2". J. Endocrinol. 159 (1): 53–60. PMID 9795341.CS1 maint: Multiple names: authors list (link)
• Franco PJ, Farooqui M, Seto E, Wei LN (2001). "The orphan nuclear receptor TR2 interacts directly with both class I and class II histone deacetylases". Mol. Endocrinol. 15 (8): 1318–28. PMID 11463856.CS1 maint: Multiple names: authors list (link)
• Tanabe O, Katsuoka F, Campbell AD; et al. (2002). "An embryonic/fetal beta-type globin gene repressor contains a nuclear receptor TR2/TR4 heterodimer". EMBO J. 21 (13): 3434–42. doi:10.1093/emboj/cdf340. PMID 12093744.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hu YC, Shyr CR, Che W; et al. (2002). "Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor". J. Biol. Chem. 277 (37): 33571–9. doi:10.1074/jbc.M203531200. PMID 12093804.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Inui S, Lee YF, Chang E; et al. (2003). "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". J. Dermatol. Sci. 31 (1): 65–71. PMID 12615366.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Franco PJ, Li G, Wei LN (2004). "Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase". Mol. Cell. Endocrinol. 206 (1–2): 1–12. PMID 12943985.CS1 maint: Multiple names: authors list (link)
• Mu X, Chang C (2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". Prostate. 57 (2): 129–33. doi:10.1002/pros.10282. PMID 12949936.
• Li G, Franco PJ, Wei LN (2003). "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2". Biochem. Biophys. Res. Commun. 310 (2): 384–90. PMID 14521922.CS1 maint: Multiple names: authors list (link)
• Lin YL, Wang YH, Lee HJ (2006). "Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A". Biochem. Biophys. Res. Commun. 350 (2): 430–6. doi:10.1016/j.bbrc.2006.09.061. PMID 17010934.CS1 maint: Multiple names: authors list (link)