Syndrome of inappropriate antidiuretic hormone natural history, complications and prognosis: Difference between revisions
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{{Syndrome of inappropriate antidiuretic hormone}} | {{Syndrome of inappropriate antidiuretic hormone}} | ||
{{CMG}}; {{AE}} {{Vbe}} | {{CMG}}; {{AE}}{{Vbe}} | ||
==Overview== | ==Overview== | ||
The [[symptoms]] of SIADH can occur at any age. If left untreated, it can lead to [[complications]], such as [[confusion]], [[seizures]], [[stupor]], and [[coma]]. Some of the [[complications]] of SIADH treatment are include [[cerebral edema]] and [[central pontine myelinolysis]], which are seen with rapid [[sodium]] correction. The prognosis of SIADH depends primarily on its cause. If the cause is [[drug|medications]], SIADH usually improves after discontinuing the [[drug|medications]]. SIADH secondary to an [[infection]], improves with the treatment of the [[infection]]. SIADH secondary to [[cancers]], has poor outcome. [[Patients]] with SIADH have different signs, symptoms and [[prognosis]] depending on the [[etiology]] of SIADH. Serum [[sodium]] concentration at short-term follow-up is predictive of long-term survival. | |||
The [[symptoms]] of | ==Natural History, Complications, and Prognosis== | ||
===Natural History=== | |||
*The [[symptoms]] of SIADH can occur at any age. | |||
== | ===Complications=== | ||
*[[complications]] of SIADH include: | |||
*[[ | **[[Confusion]] | ||
*[[ | **[[Seizure]] | ||
*[[ | **[[Stupor]] | ||
**[[Coma]] | |||
*Some of the [[complications]] of SIADH treatment are include: | |||
**[[Cerebral edema]] | |||
**[[Central pontine myelinolysis]] | |||
*[[ | |||
*[[Central pontine myelinolysis]] | |||
===Prognosis=== | |||
*The prognosis of SIADH depends primarily on its cause. | |||
**If the cause is [[drug|medications]], SIADH usually improves after discontinuing the medication. | |||
**SIADH secondary to an [[infection]], improves with the treatment of the [[infection]]. | |||
**SIADH secondary to [[cancers]], has poor outcome. | |||
**[[Patients]] with SIADH have different signs, symptoms and [[prognosis]] depending on the [[etiology]] of SIADH. Serum [[sodium]] concentration at short-term follow-up is predictive of long-term survival. Rapid correction of serum [[sodium]] concentration can lead to various complications.<ref name="pmid27837439">{{cite journal |vauthors=Tzoulis P, Carr H, Bagkeris E, Bouloux PM |title=Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care |journal=Endocrine |volume=55 |issue=2 |pages=539–546 |year=2017 |pmid=27837439 |pmc=5272879 |doi=10.1007/s12020-016-1161-9 |url=}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Medicine]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Nephrology]] | |||
[[Category:Neurology]] | [[Category:Neurology]] | ||
[[Category: | [[Category:Up-To-Date]] | ||
Latest revision as of 00:22, 30 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
The symptoms of SIADH can occur at any age. If left untreated, it can lead to complications, such as confusion, seizures, stupor, and coma. Some of the complications of SIADH treatment are include cerebral edema and central pontine myelinolysis, which are seen with rapid sodium correction. The prognosis of SIADH depends primarily on its cause. If the cause is medications, SIADH usually improves after discontinuing the medications. SIADH secondary to an infection, improves with the treatment of the infection. SIADH secondary to cancers, has poor outcome. Patients with SIADH have different signs, symptoms and prognosis depending on the etiology of SIADH. Serum sodium concentration at short-term follow-up is predictive of long-term survival.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of SIADH can occur at any age.
Complications
- complications of SIADH include:
- Some of the complications of SIADH treatment are include:
Prognosis
- The prognosis of SIADH depends primarily on its cause.
- If the cause is medications, SIADH usually improves after discontinuing the medication.
- SIADH secondary to an infection, improves with the treatment of the infection.
- SIADH secondary to cancers, has poor outcome.
- Patients with SIADH have different signs, symptoms and prognosis depending on the etiology of SIADH. Serum sodium concentration at short-term follow-up is predictive of long-term survival. Rapid correction of serum sodium concentration can lead to various complications.[1]
References
- ↑ Tzoulis P, Carr H, Bagkeris E, Bouloux PM (2017). "Improving care and outcomes of inpatients with syndrome of inappropriate antidiuresis (SIAD): a prospective intervention study of intensive endocrine input vs. routine care". Endocrine. 55 (2): 539–546. doi:10.1007/s12020-016-1161-9. PMC 5272879. PMID 27837439.