Syndrome of inappropriate antidiuretic hormone history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The main | The main pathology in patients with [[SIADH]] is excessive[[ water]] retention and [[hyponatremia]]. [[Symptoms]] of SIADH depend on the level of [[sodium]] in the blood and the rate at which the level of [[sodium ]]falls. Symptoms may be non-specific such as generalised [[fatigue]] and weakness but if severe, symptoms such as [[irritability]], [[nausea]], [[vomiting]], [[muscle weakness]] and [[cramps]], [[loss of appetite]], [[confusion]], [[personality changes]], [[hallucinations]], [[seizures]], [[stupor]] and [[coma]] may be seen. | ||
==History and Symptoms== | ==History and Symptoms== | ||
Revision as of 19:00, 29 August 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
The main pathology in patients with SIADH is excessivewater retention and hyponatremia. Symptoms of SIADH depend on the level of sodium in the blood and the rate at which the level of sodium falls. Symptoms may be non-specific such as generalised fatigue and weakness but if severe, symptoms such as irritability, nausea, vomiting, muscle weakness and cramps, loss of appetite, confusion, personality changes, hallucinations, seizures, stupor and coma may be seen.
History and Symptoms
Symptoms vary, depending on the degree of abnormality in the serum sodium concentration and the rate at which the concentration falls. Usual symptoms include:
- Nausea, vomiting
- Loss of appetite
- Fatigue and weakness
- Irritability
- Personality changes, such as combativeness.
- Seizures
- Confusion
- Hallucinations
- Stupor
- Coma[1]
Other disorders may have the above symptoms too. If the patient experiences the above symptoms, he/she should immediately consult their health care provider.
References
- ↑ Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, Decaux G, Fenske W, Hoorn EJ, Ichai C, Joannidis M, Soupart A, Zietse R, Haller M, van der Veer S, van Biesen W, Nagler E, Gonzalez-Espinoza L, Ortiz A (2017). "Hyponatraemia diagnosis and treatment clinical practice guidelines". Nefrologia. 37 (4): 370–380. doi:10.1016/j.nefro.2017.03.021. PMID 28619670.