Sjögren's syndrome history and symptoms

Jump to navigation Jump to search

Sjögren's syndrome Microchapters

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Sjögren's syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Sjögren's syndrome history and symptoms On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Sjögren's syndrome history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Sjögren's syndrome history and symptoms

CDC on Sjögren's syndrome history and symptoms

Sjögren's syndrome history and symptoms in the news

Blogs on Sjögren's syndrome history and symptoms

Directions to Hospitals Treating Sjögren's syndrome

Risk calculators and risk factors for Sjögren's syndrome history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]


Overview

History and Symptoms

  • The most common symptoms of Sjögren's syndrome include ocular and oral symptoms.

History

Patients with Sjögren's syndrome may have a positive history of:

  • Rheumatoid arthritis (RA)
  • Systemic lupus erythematous (SLE)
  • Non-Hodgkin B-cell lymphoma

Common Symptoms

Common symptoms of Sjögren's syndrome include:[1][2][3][4][1][5][6][7][8][9][10][11]

  • Skin manifestations
    • Xerosis
    • Purpura, associated with vascular or hematologic abnormalities
    • Raynaud phenomenon
    • Cutaneous vasculitis
    • Annular erythema
    • Erythema nodosum
    • Livedo reticularis
    • Lichen planus
    • Vitiligo
    • Cutaneous amyloidosis
    • Granuloma annulare
    • Angular cheilitis
    • Eyelid dermatitis
  • Musculoskeletal manifestations
    • Arthralgia
    • Arthritis
    • Myopathy
  • Fatigue and fibromyalgia
  • Pulmonary symptoms
    • Dryness of the tracheobronchial mucosa(xerotrachea)
    • Dry cough
    • Recurrent bronchitis
    • Pneumonitis (infectious or noninfectious)
  • Gastrointestinal manifestations
    • Dysphagia
    • Nausea
    • Dyspepsia and gastritis
    • Celiac disease
    • Hepatic abnormalities
    • subclinical pancreatic disease
    • Dyspnea from interstitial lung disease
  • Cardiac involvement
    • Pericarditis
    • Pulmonary hypertension
    • Dysfunction of autonomic control of blood pressure
    • Myocardial disease
  • Neurologic and psychiatric symptoms
    • Myelopathy
    • Optic neuropathy
    • Seizures
    • Cognitive dysfunction
    • Encephalopathy
    • Painful sensory neuropathy
    • Sensory ataxic neuropathy
    • Pure sensory trigeminal neuropathy
    • Axonal sensorimotor polyneuropathy
    • Mononeuritis multiplex
    • Multiple cranial neuropathies
    • Radiculoneuropathy
    • Autonomic neuropathy
    • Depression
  • Urogenital manifestations
    • Interstitial nephritis
    • Interstitial cystitis
    • Vulvovaginal dryness, pruritus, and dyspareunia
  • Parotitis
  • Cutaneous vasculitis

References

  1. 1.0 1.1 Kittridge A, Routhouska SB, Korman NJ (2011). "Dermatologic manifestations of Sjögren syndrome". J Cutan Med Surg. 15 (1): 8–14. doi:10.2310/7750.2010.09033. PMID 21291650.
  2. Roguedas AM, Misery L, Sassolas B, Le Masson G, Pennec YL, Youinou P (2004). "Cutaneous manifestations of primary Sjögren's syndrome are underestimated". Clin. Exp. Rheumatol. 22 (5): 632–6. PMID 15485020.
  3. Baimpa E, Dahabreh IJ, Voulgarelis M, Moutsopoulos HM (September 2009). "Hematologic manifestations and predictors of lymphoma development in primary Sjögren syndrome: clinical and pathophysiologic aspects". Medicine (Baltimore). 88 (5): 284–93. doi:10.1097/MD.0b013e3181b76ab5. PMID 19745687.
  4. Theander E, Henriksson G, Ljungberg O, Mandl T, Manthorpe R, Jacobsson LT (June 2006). "Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictors". Ann. Rheum. Dis. 65 (6): 796–803. doi:10.1136/ard.2005.041186. PMC 1798187. PMID 16284097.
  5. Amezcua-Guerra LM, Hofmann F, Vargas A, Rodriguez-Henriquez P, Solano C, Hernández-Díaz C, Castillo-Martinez D, Ventura-Ríos L, Gutiérrez M, Pineda C (2013). "Joint involvement in primary Sjögren's syndrome: an ultrasound "target area approach to arthritis"". Biomed Res Int. 2013: 640265. doi:10.1155/2013/640265. PMC 3722787. PMID 23936829.
  6. Kanellopoulos P, Baltoyiannis C, Tzioufas AG (April 2002). "Primary Sjögren's syndrome associated with inclusion body myositis". Rheumatology (Oxford). 41 (4): 440–4. PMID 11961175.
  7. Pérez B, Kraus A, López G, Cifuentes M, Alarcón-Segovia D (November 1995). "Autoimmune thyroid disease in primary Sjögren's syndrome". Am. J. Med. 99 (5): 480–4. PMID 7485204.
  8. Ramirez-Mata M, Pena Ancira FF, Alarcon-Segovia D (March 1976). "Abnormal esophageal motility in primary Sjögren's syndrome". J. Rheumatol. 3 (1): 63–9. PMID 1271390.
  9. Lehrer S, Bogursky E, Yemini M, Kase NG, Birkenfeld A (March 1994). "Gynecologic manifestations of Sjögren's syndrome". Am. J. Obstet. Gynecol. 170 (3): 835–7. PMID 8141212.
  10. Binder A, Snaith ML, Isenberg D (August 1988). "Sjögren's syndrome: a study of its neurological complications". Br. J. Rheumatol. 27 (4): 275–80. PMID 3261608.
  11. Ramos-Casals M, Font J, Garcia-Carrasco M, Brito MP, Rosas J, Calvo-Alen J, Pallares L, Cervera R, Ingelmo M (July 2002). "Primary Sjögren syndrome: hematologic patterns of disease expression". Medicine (Baltimore). 81 (4): 281–92. PMID 12169883.

Template:WS Template:WH