Sjögren's syndrome history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]


Overview

History and Symptoms

  • The majority of patients with [disease name] are asymptomatic.

OR

  • The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
  • Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History

Patients with [disease name]] may have a positive history of:

  • [History finding 1]
  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of Sjögren's syndrome include:

  • Skin manifestations
    • Xerosis
    • Purpura, associated with vascular or hematologic abnormalities
    • Raynaud phenomenon
    • Cutaneous vasculitis
    • Annular erythema
    • Erythema nodosum
    • Livedo reticularis
    • Lichen planus
    • Vitiligo
    • Cutaneous amyloidosis
    • Granuloma annulare
    • Angular cheilitis
    • Eyelid dermatitis
  • Musculoskeletal manifestations
    • Arthralgia
    • Arthritis
    • Myopathy
  • Fatigue and fibromyalgia
  • Pulmonary symptoms
    • Dryness of the tracheobronchial mucosa(xerotrachea)
    • Dry cough
    • Recurrent bronchitis
    • Pneumonitis (infectious or noninfectious)
  • Gastrointestinal manifestations
    • Dysphagia
    • Nausea
    • Dyspepsia and gastritis
    • Celiac disease
    • Hepatic abnormalities
    • subclinical pancreatic disease
    • Dyspnea from interstitial lung disease
  • Cardiac involvement
    • Pericarditis
    • Pulmonary hypertension
    • Dysfunction of autonomic control of blood pressure
    • Myocardial disease
  • Neurologic and psychiatric symptoms
    • Myelopathy
    • Optic neuropathy
    • Seizures
    • Cognitive dysfunction
    • Encephalopathy
    • Painful sensory neuropathy
    • Sensory ataxic neuropathy
    • Pure sensory trigeminal neuropathy
    • Axonal sensorimotor polyneuropathy
    • Mononeuritis multiplex
    • Multiple cranial neuropathies
    • Radiculoneuropathy
    • Autonomic neuropathy
    • Depression
  • Urogenital manifestations
    • Interstitial nephritis
    • Interstitial cystitis
    • Vulvovaginal dryness, pruritus, and dyspareunia
  • Parotitis

References

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