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==Differential Diagnosis==
==Differentiating Leukocytosis from Other Diseases==
 
{|
'''Abbreviations:''' [[Arterial blood gas|ABG]] = [[Arterial blood gas|Arterial blood gases]], [[BUN]] = [[Blood urea nitrogen]], [[Complete blood count|CBC]] = [[Complete blood count]], [[Computed tomography|CT]] = [[Computed tomography]], CRP = C - reactive protein, [[ECG]] = [[Electrocardiogram]], ESR = [[Erythrocyte sedimentation rate]], IVP  = Intravenous pyelography, [[Renal function|KFT]] = [[Renal function tests|Kidney function test]], GI = Gastrointestinal, GFR = [[Glomerular filtration rate]], [[Magnetic resonance imaging|MRI]] = [[Magnetic resonance imaging]], [[PT]] = [[Prothrombin time]]
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
 
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
{|  
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! colspan="2" rowspan="3" style="background:#4479BA; color: #FFFFFF;" |Etiology
! colspan="4" rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Mechanism
! colspan="9" style="background:#4479BA; color: #FFFFFF;" |Clinical manifestations
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
! colspan="11" style="background:#4479BA; color: #FFFFFF;" |Paraclinical findings
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
! rowspan="3" style="background:#4479BA; color: #FFFFFF;" |Comments
! colspan="11" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestations
! colspan="8" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para−clinical findings
! colspan="1" rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
|-
! colspan="9" style="background:#4479BA; color: #FFFFFF;" |Symptoms and signs
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! colspan="6" style="background:#4479BA; color: #FFFFFF;" |Lab findings
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! colspan="5" style="background:#4479BA; color: #FFFFFF;" |Imaging
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
| colspan="6" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Signs
|-
|-
! align="center" style="background:#4479BA; color: #FFFFFF;" |Fatigue/
! colspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
Lethargy
! align="center" style="background:#4479BA; color: #FFFFFF;" |Thirst
! align="center" style="background:#4479BA; color: #FFFFFF;" |Dizziness/
Confusion
! align="center" style="background:#4479BA; color: #FFFFFF;" |Muscle weakness/
cramp
! align="center" style="background:#4479BA; color: #FFFFFF;" |Somatic/
visceral pain
! align="center" style="background:#4479BA; color: #FFFFFF;" |Vomiting
! align="center" style="background:#4479BA; color: #FFFFFF;" |Diarrhea
! align="center" style="background:#4479BA; color: #FFFFFF;" |Tachypnea
! align="center" style="background:#4479BA; color: #FFFFFF;" |Edema
! align="center" style="background:#4479BA; color: #FFFFFF;" |Blood indices
! align="center" style="background:#4479BA; color: #FFFFFF;" |Renal Funtion test
! align="center" style="background:#4479BA; color: #FFFFFF;" |Electrolytes
! align="center" style="background:#4479BA; color: #FFFFFF;" |Urine analysis
! align="center" style="background:#4479BA; color: #FFFFFF;" |ABG
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
! align="center" style="background:#4479BA; color: #FFFFFF;" |Ultrasound
! align="center" style="background:#4479BA; color: #FFFFFF;" |X-ray
! align="center" style="background:#4479BA; color: #FFFFFF;" |CT
! align="center" style="background:#4479BA; color: #FFFFFF;" |MRI
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
|-
|-
! rowspan="22" style="background: #DCDCDC; padding: 5px; text-align: center;" |Prerenal causes
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Alcohol poisoning]]
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Increased bone marrow production
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +
! colspan="1" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +/-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +/-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +/-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[PT]]
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]] (isopropyl [[alcohol]])
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |CBC
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]]
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Bicarbonate|HCO3]]
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Liver function tests|LFT]]
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thiamine]] must be given to prevent [[Wernicke's encephalopathy]]
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Aspergillosis|'''Aspergillosis''']]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Allergy test]], ↑[[IgE]] (>1000 IU/dl), Direct visualization of [[Hyphae|fungal hyphae]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Pulmonary infiltrates, [[Mucus|Mucus plug]], Mass in the upper lobe surrounded by a crescent of air, Solitary or multiple cavities
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Halo sign, Wedge-shaped pulmonary [[infarction]], [[Granuloma]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Polymerase chain reaction|Polymerase chain reaction (PCR)]]
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cholera|'''Cholera''']]<ref name="pmid4809112">{{cite journal |vauthors=Cash RA, Music SI, Libonati JP, Snyder MJ, Wenzel RP, Hornick RB |title=Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum |journal=J. Infect. Dis. |volume=129 |issue=1 |pages=45–52 |date=January 1974 |pmid=4809112 |doi= |url=}}</ref>
! rowspan="7" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hematologic
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
! align="center" style="background:#DCDCDC;" |[[Granulocytosis|Hereditary neutrophilia]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
* Unknown
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
* Germline mutation in [[CSF3R]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + | +
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + | --
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + | +
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Leukocytosis]], ↑[[Hematocrit|HCT]]
| align="center" style="background:#F5F5F5;" + | -
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |Rare [[Dominance relationship|autosomal dominant]] genetic disorder
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]], ↑[[Ca]], ↑[[Mg]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
* Positive family history
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Lactate]], ↓[[Bicarbonate|HCO3]]
| align="center" style="background:#F5F5F5;" + |Normal
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Stool PCR, Stool culture, Serotyping
| align="center" style="background:#F5F5F5;" + |-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |Nl
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |-
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |+
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |-
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |-
| align="center" style="background:#F5F5F5;" + |-
| align="center" style="background:#F5F5F5;" + |↑
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |
* Normal [[Granulocyte|granulocytes]]
* [[Histiocyte|Histiocytes]] of Gaucher type
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |[[Genetics|Genetic]] study
| align="center" style="background:#F5F5F5;" + |
* High [[leukocyte alkaline phosphatase]]
* Progress to [[leukemia]]
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Congestive heart failure]] (CHF)
! align="center" style="background:#DCDCDC;" |Hereditary chronic neutrophilia
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | +
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Anemia]], [[Leukocytosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]], ↑[[Potassium|K]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Lactate]], ↓[[Bicarbonate|HCO3]],
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[BNP]], ↑[[Troponin]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Cardiomegaly]], [[Pulmonary hypertension]], [[Pleural effusions]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Pulmonary edema]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Valvular heart disease]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Decreased [[ejection fraction]] in [[echocardiography]], Heart function and damage in nuclear imaging
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Dehydration]]
! align="center" style="background:#DCDCDC;" |[[Myeloproliferative neoplasm|Myeloproliferative neoplasms]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]], ↑[[Potassium|K]], ↓[[Chloride|Cl]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Ketone]]s and [[glucose]], ↑Urine specific gravity
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Lactate]], ↓[[Bicarbonate|HCO3]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Hypoglycemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Diarrhea]] and/or [[vomiting]]
! align="center" style="background:#DCDCDC;" |[[Polycythemia vera]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Leukocytosis]] with predominant [[neutrophilia]], ↑ [[ESR]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Ketones]], Organic acids, [[Porphobilinogen]], [[Aminolevulinic acid]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Stool [[anion gap]], Stool pH < 5.5, Stool culture, Serotyping, Enzyme immunoassay ([[rotavirus]] or [[adenovirus]]), [[Liver function tests|LFT]], [[Amylase]], [[Lipase]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Normal
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drugs]]/[[Toxin|toxins]]
! align="center" style="background:#DCDCDC;" |[[Microangiopathic hemolytic anemia]] (MAHA)
 
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]], ↑[[Creatine kinase|CK]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Potassium|K]], ↓[[Magnesium|Mg]], ↓[[Ca]], ↓[[Phosphate|P]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Ingested drug, [[Glucose]], [[Aminoacid]], [[Phosphate]], [[Ketone]], [[Hyaline cast]], [[RBC]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Lactate]], [[Metabolic acidosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Toxicology]], Rapid [[immunoassay]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Nephropathy]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Radioopaque substances, Ingested drug packets
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Esophageal varices|'''Esophageal varices bleeding''']]
! align="center" style="background:#DCDCDC;" |Leukoerythroblastosis
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Normocytic normochromic anemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Velocity and direction of [[portal]] flow
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Abnormal opacities  outside of[[esophageal]] wall, Posterior [[mediastinal]] or intraparenchymal mass, Dilated [[azygous vein]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Entire portal venous system
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Portrays [[esophageal varices]] as flow voids
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Portal hypertension and [[esophageal varices]] in [[positron emission tomography]], Flexible [[endoscope]], [[Barium swallow]] of snake-like filling defects
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Heart disease]]
! align="center" style="background:#DCDCDC;" |Immune thrombocytopenia
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[ESR]] and [[CRP]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Throat culture]], Rapid streptococcal antigen test, Hyperoxia test, [[Pulse oximetry]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Cardiomegaly]], [[Dextrocardia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Ventricular dysfunction]], Left and right ventricular [[hypertrophy]], Valvular disease in [[echocardiography]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemorrhage]]
! rowspan="12" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Immunology/
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
Rheumatology
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous increased bone marrow production
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive increased bone marrow production
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Normocytic normochromic anemia]], ↑[[PT]], ↑[[PTT]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Sodium|Na]], ↑[[Chloride|Cl]], ↓[[Ca]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Metabolic acidosis]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Peritoneal cavity fluid in [[FAST]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Bilateral opacities in the lung field, [[Hemothorax]], Hemoperitoneum, Ruptured [[abdominal aortic aneurysm]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Intrathoracic, intra-abdominal, and retroperitoneal [[bleeding]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Source of [[bleeding]] in the upper GI in [[Esophagogastroduodenoscopy|EGD]], [[Angiography]]
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other signs
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hemolysis]]
! align="center" style="background:#DCDCDC;" |[[Leukocyte adhesion deficiency]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Thrombocytopenia|Thrombocytopenia,]] [[Microcytic anemia|Microcytic hypochromic anemia]], ↑RDW, ↑[[Reticulocyte|Retic]] count
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[LDH]], ↓[[Haptoglobin]], ↑Unconjugated [[bilirubin]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Hepatomegaly]],[[Splenomegaly]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! align="center" style="background:#4479BA; color: #FFFFFF;" |Etiology
! align="center" style="background:#DCDCDC;" |Cryopyrin-associated periodic syndromes
! align="center" style="background:#4479BA; color: #FFFFFF;" |Fatigue/
| align="center" style="background:#F5F5F5;" + |
Lethargy
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Thirst
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Dizziness/
| align="center" style="background:#F5F5F5;" + |
Confusion
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Muscle weakness/
| align="center" style="background:#F5F5F5;" + |
cramp
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Somatic/
| align="center" style="background:#F5F5F5;" + |
visceral pain
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Vomiting
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Diarrhea
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Tachypnea
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Edema
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Blood indices
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Renal Funtion test
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Electrolytes
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Urine analysis
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |ABG
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Ultrasound
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |X-ray
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |CT
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |MRI
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
| align="center" style="background:#F5F5F5;" + |
! align="center" style="background:#4479BA; color: #FFFFFF;" |Comments
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hepatorenal syndrome]]
! align="center" style="background:#DCDCDC;" |[[Rheumatoid arthritis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Leukocytosis]], ↑[[PT]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Glomerular filtration rate|GFR]], ↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Proteinuria]],  [[Sodium|Na]] < 10 mEq/L, [[Urine osmolality]] > [[plasma osmolality]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Alpha fetoprotein|Alpha feto-protein]], [[Cryoglobulinemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Exclude [[hydronephrosis]] and intrinsic renal disease
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Right ventricular preload, ventricular filling pressures, and cardiac function in [[echocardiography]]
| align="center" style="background:#F5F5F5;" + |
| -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Cardiomyopathy|Ischemic cardiomyopathy]]
! align="center" style="background:#DCDCDC;" |[[Juvenile rheumatoid arthritis|Juvenile onset rheumatoid arthritis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Anemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Sodium|Na]], ↓[[Potassium|K]], ↓[[Magnesium|Mg]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Troponin]], [[Creatine kinase]], [[Creatine kinase]] - MB, [[Brain natriuretic peptide|BNP]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Abnormal cardiac silhouette
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Biventricular volume, Wall motion abnormality, Myocardial perfusion, [[Hypertrophic cardiomyopathy]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Mid-wall [[fibrosis]] in [[MRI]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Ejection fraction ≤35%, Pulmonary embolism, Right ventricular dilation or [[pericardial effusion]] with tamponade in echocardiography
| align="center" style="background:#F5F5F5;" + |
| -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Liver cirrhosis]]
! align="center" style="background:#DCDCDC;" |[[Still's disease|Adult Still's disease]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Liver function tests|LFT]], [[Aspartate aminotransferase]] to [[platelet]] ratio, FibroTest/FibroSure, Hepascore, FibroSpectatio
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Portal blood flow velocity, [[Hepatic artery]] enlargement, Multifocal  lesions or masses, Hepatic contour, [[Ascites]], [[Splenomegaly]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Bowel perforation]], [[Gynecomastia]], [[Azygos vein]] enlargement, [[Pleural effusion]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Morphologic changes in the liver, Collaterals and shunts, Hyperattenuating nodule of [[hepatocellular carcinoma]], [[Portal vein thrombosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Vacular patency, Tumor invasion, [[Portal vein thrombosis]], [[Steatosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Hepatic]] function and [[portal hypertension]] in nuclear imaging, [[Hepatic]] perfusion and the development of [[shunt]]s and [[tumor]]s in angiography
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Irreversible and a transplant is usually needed
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Malignant hypertension]]
! align="center" style="background:#DCDCDC;" |[[Kawasaki disease]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Microangiopathic hemolytic anemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Sodium|Na]], ↑[[Potassium|K]], ↑[[Phosphate|P]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Proteinuria]], [[Microscopic hematuria]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Acidosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Cardiac enzymes]], Urinary [[catecholamines]], [[TSH]], ↑[[Renin]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Cardiomegaly, [[Pulmonary edema]], Rib notching, [[Aortic coarctation]], Mediastinal widening, [[Aortic dissection]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Left atrial enlargement and left ventricular [[hypertrophy|hypertrophy in]] [[echocardiography]]
| align="center" style="background:#F5F5F5;" + |
| -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Myocarditis]]
! align="center" style="background:#DCDCDC;" |[[Inflammatory bowel disease|IBD]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Leukocytosis]] ([[eosinophilia]]),↑[[ESR]] and [[CRP]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Cardiac enzymes]], Viral antibodies
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Inflammatory [[edema]], Degree of scarring
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Endomyocardial biopsy]], [[Echocardiography]], [[Scintigraphy]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Peritonitis]]
! align="center" style="background:#DCDCDC;" |[[Sarcoidosis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Leukocytosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Ascitic fluid [[neutrophil]] count > 500 cells/µL
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Polycythemia]]
! align="center" style="background:#DCDCDC;" |[[Hepatitis|Chronic hepatitis]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[RBC]], ↑[[Hematocrit|HCT]], ↑[[Hemoglobin|HGB]], [[Thrombocytosis]], [[Leukocytosis]], ↑[[PT]] and [[aPTT]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Erythropoietin]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Hyperuricemia]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Splenomegaly]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Phlebotomy]] is the usual treatment
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Respiratory distress syndrome]]
! align="center" style="background:#DCDCDC;" |[[Sweet's syndrome|Sweet syndrome]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Metabolic acidosis|Metabolic]] and [[Metabolic acidosis|respiratory acidosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Pulse oximetry]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Bilateral, diffuse, reticular granular or ground-glass appearance +/- [[Cardiomegaly]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Patent ductus arteriosus]] [[hypertrophy|in]] [[echocardiography]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Shock]]
! align="center" style="background:#DCDCDC;" |[[Gout|Acute gout]]
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>+/-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |<nowiki>-</nowiki>
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Hematocrit|HCT]], ↑[[PT]] and [[aPTT]], [[Eosinophilia]], [[Leukocytosis]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↓[[Glomerular filtration rate|GFR]], ↑[[Blood urea nitrogen|BUN]], ↑[[Cr]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |↑[[Lactate]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Liver function tests|LFT]],  ↑[[BNP]], ↑[[Troponin]], [[D-dimer]], [[Fibrinogen]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Pulmonary embolism]], [[Pericardial effusion]], [[Cardiac tamponade]], [[Pneumothorax]], Thoracic or [[abdominal aortic aneurysm]] in RUSH (Rapid Ultrasound for Shock and Hypotension)
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |[[Pneumonia]], [[Pneumothorax]], [[Pulmonary edema]], Widened [[mediastinum]], Free air under the [[diaphragm]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |Traumatic brain injury, [[Stroke]], Spinal injury, [[Pneumonia]], [[Pneumothorax]], Ruptured [[aneurysm]], [[Aortic dissection]], [[Pulmonary embolism]]
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" |NA
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| style="background: #F5F5F5; padding: 5px; text-align: center;" | -
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
|-
! rowspan="6" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infection
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other signs
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
! align="center" style="background:#DCDCDC;" |[[Infection|Acute bacterial]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |toxic granulations, Döhle bodies, and cytoplasmic vacuoles in neutrophils
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Infection|Chronic infection]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Infection|Viral infection]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Granuloma|Granulomatous]] infections
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Bronchiectasis]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Metabolic
! align="center" style="background:#DCDCDC;" |[[Diabetic coma]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Acidosis]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Thyroid storm]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Cushing's syndrome|Hypercortisolism]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Seizure|Seizures]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! rowspan="7" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Medication
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other signs
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
! align="center" style="background:#DCDCDC;" |[[Steroid|Steriod]]
| align="center" style="background:#F5F5F5;" + |
* Release of granulocytes from the bone marrow
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |Myeloid growth factors
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Lithium]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Cytokine|Cytokines]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Catecholamine|Catecholamines]] ([[epinephrine]])
| align="center" style="background:#F5F5F5;" + |
* Stimulation of bone marrow myelopoiesis
* Egress into the circulation
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Tretinoin|ATRA]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! rowspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other signs
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
! align="center" style="background:#DCDCDC;" |[[Allergy]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |Post [[splenectomy]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Down syndrome]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Smoking|Cigarette smoking]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Stress (medicine)|Stress]]/[[Physical exercise|exercise]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Infant|Infancy]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Pregnancy]]
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Platelet]] clumping
| align="center" style="background:#F5F5F5;" + |Spurious
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! align="center" style="background:#DCDCDC;" |[[Cryoglobulinemia|Mixed cryoglobulinemia]]
| align="center" style="background:#F5F5F5;" + |Spurious
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
| align="center" style="background:#F5F5F5;" + |
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Category
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Condition
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physiologic
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Autonomous increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Reactive increased bone marrow production
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demargination of peripheral blood neutrophils
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Congenital
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Acquried
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Appearance
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Asplenia
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hepatosplenomegaly
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lymphadenopathy
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Joint redness
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other signs
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |WBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HB
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Plt
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |PBS
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bone marrow exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |ESR/CRP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BUN/Cr
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LFT
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|}
|}
<references />

Latest revision as of 21:38, 17 September 2018

Differentiating Leukocytosis from Other Diseases

Category Condition Etiology Mechanism Congenital Acquried Clinical manifestations Para−clinical findings Gold standard Associated findings
Demography History Symptoms Signs
Lab Findings
Physiologic Increased bone marrow production Demargination of peripheral blood neutrophils Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other CBC PBS Bone marrow exam ESR/CRP BUN/Cr LFT
Autonomous Reactive WBC HB Plt
Hematologic Hereditary neutrophilia
  • Unknown
  • Germline mutation in CSF3R
- + -- - + - Rare autosomal dominant genetic disorder
  • Positive family history
Normal - - Nl - + - - - Nl Nl Nl Nl Nl Nl Genetic study
Hereditary chronic neutrophilia
Myeloproliferative neoplasms
Polycythemia vera
Microangiopathic hemolytic anemia (MAHA)
Leukoerythroblastosis
Immune thrombocytopenia
Immunology/

Rheumatology

Condition Etiology Physiologic Autonomous increased bone marrow production Reactive increased bone marrow production Demargination of peripheral blood neutrophils Congenital Acquried Demography History Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other signs WBC HB Plt PBS Bone marrow exam ESR/CRP BUN/Cr LFT Gold standard Associated findings
Leukocyte adhesion deficiency
Cryopyrin-associated periodic syndromes
Rheumatoid arthritis
Juvenile onset rheumatoid arthritis
Adult Still's disease
Kawasaki disease
IBD
Sarcoidosis
Chronic hepatitis
Sweet syndrome
Acute gout
Infection Condition Etiology Physiologic Autonomous increased bone marrow production Reactive increased bone marrow production Demargination of peripheral blood neutrophils Congenital Acquried Demography History Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other signs WBC HB Plt PBS Bone marrow exam ESR/CRP BUN/Cr LFT Gold standard Associated findings
Acute bacterial toxic granulations, Döhle bodies, and cytoplasmic vacuoles in neutrophils
Chronic infection
Viral infection
Granulomatous infections
Bronchiectasis
Metabolic Diabetic coma
Acidosis
Thyroid storm
Hypercortisolism
Seizures
Medication Condition Etiology Physiologic Autonomous increased bone marrow production Reactive increased bone marrow production Demargination of peripheral blood neutrophils Congenital Acquried Demography History Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other signs WBC HB Plt PBS Bone marrow exam ESR/CRP BUN/Cr LFT Gold standard Associated findings
Steriod
  • Release of granulocytes from the bone marrow
Myeloid growth factors
Lithium
Cytokines
Catecholamines (epinephrine)
  • Stimulation of bone marrow myelopoiesis
  • Egress into the circulation
ATRA
Other Condition Etiology Physiologic Autonomous increased bone marrow production Reactive increased bone marrow production Demargination of peripheral blood neutrophils Congenital Acquried Demography History Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other signs WBC HB Plt PBS Bone marrow exam ESR/CRP BUN/Cr LFT Gold standard Associated findings
Allergy
Post splenectomy
Down syndrome
Cigarette smoking
Stress/exercise
Infancy
Pregnancy
Platelet clumping Spurious
Mixed cryoglobulinemia Spurious
Category Condition Etiology Physiologic Autonomous increased bone marrow production Reactive increased bone marrow production Demargination of peripheral blood neutrophils Congenital Acquried Demography History Appearance Fever Abdominal pain BP Asplenia Hepatosplenomegaly Lymphadenopathy Joint redness Other signs WBC HB Plt PBS Bone marrow exam ESR/CRP BUN/Cr LFT Gold standard Associated findings