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==MRI==
==MRI==
*MRI imaging study of retinoblastoma first introduced in 1980.<ref name="Schueler2003">{{cite journal|last1=Schueler|first1=A O|title=High resolution magnetic resonance imaging of retinoblastoma|journal=British Journal of Ophthalmology|volume=87|issue=3|year=2003|pages=330–335|issn=00071161|doi=10.1136/bjo.87.3.330}}</ref>
*This method is used as an extra diagnostic method to CT scan in suspected retinoblastoma cases especially in those whose CT scan imaging is doubtful for the presence of extra-ocular extension.<ref name="pmid22988349">{{cite journal |vauthors=Meel R, Radhakrishnan V, Bakhshi S |title=Current therapy and recent advances in the management of retinoblastoma |journal=Indian J Med Paediatr Oncol |volume=33 |issue=2 |pages=80–8 |date=April 2012 |pmid=22988349 |pmc=3439795 |doi=10.4103/0971-5851.99731 |url=}}</ref>
[[MRI]] is the modality of choice for pre-treatment staging on retinoblastoma.
[[MRI]] is the modality of choice for pre-treatment staging on retinoblastoma.
*The MRI features of retinoblastoma include:<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015</ref>
*The MRI features of retinoblastoma include:<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015</ref>

Revision as of 19:01, 3 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [3]

Overview

On head and neck MRI, retinoblastoma is characterized by isointense to hypointense mass on T1-weighted MRI and hyperintense mass on T2-weighted MRI.[1]

MRI

  • MRI imaging study of retinoblastoma first introduced in 1980.[2]
  • This method is used as an extra diagnostic method to CT scan in suspected retinoblastoma cases especially in those whose CT scan imaging is doubtful for the presence of extra-ocular extension.[3]




MRI is the modality of choice for pre-treatment staging on retinoblastoma.

  • The MRI features of retinoblastoma include:[1]
MRI component Features
T1
  • Intermediate signal intensity, hyperintense c.f. vitreous
T2
  • Hypointense c.f. vitreous
T1 contrast with gadolinium
  • The mass usually enhances relatively homogeneously when small
  • Larger tumors often have areas of necrosis, rendering it heterogeneous
  • Linear enhancement of the choroid beyond the margins of the tumour should raise the possibility of choroidal involvement, although inflammation may lead to similar appearance
  • Enhancement of the anterior chamber need not represent tumour involvement, with hyperaemia, uveitis and iris neovascularisation all leading to asymmetric enhancement
  • Careful assessment of the optic disc and optic nerve should be carried out to assess for involvement
  • Extra-ocular extension through the sclera will be visible as interruption of the otherwise hypointense non-enhancing sclera by enhancing tumour
Diffusion Weighted Imaging
  • The tumour shows restricted diffusion on DWI at high b values. It exhibits low ADC values in contrast to the high intensity of the vitreous in the ADC maps
  • ADC map can be used to differentiate viable and necrotic tumour
  • DWI is valuable in evaluating the response to eye-preservation treatment
Axial MRI showing retinoblastoma[4]
T1 MRI showing retinoblastoma[4]
T2 MRI showing retinoblastoma[4]

References

  1. 1.0 1.1 Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015
  2. Schueler, A O (2003). "High resolution magnetic resonance imaging of retinoblastoma". British Journal of Ophthalmology. 87 (3): 330–335. doi:10.1136/bjo.87.3.330. ISSN 0007-1161.
  3. Meel R, Radhakrishnan V, Bakhshi S (April 2012). "Current therapy and recent advances in the management of retinoblastoma". Indian J Med Paediatr Oncol. 33 (2): 80–8. doi:10.4103/0971-5851.99731. PMC 3439795. PMID 22988349.
  4. 4.0 4.1 4.2 Image courtesy of Radswiki Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC

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