Retinoblastoma MRI: Difference between revisions

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==Overview==
==Overview==
On [[head]] and [[neck]] [[MRI]], retinoblastoma is characterized by isointense to hypointense mass on T1-weighted MRI and hyperintense mass on T2-weighted MRI.<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10 2015</ref>
On [[head]] and [[neck]] [[MRI]], retinoblastoma is characterized by isointense to hypointense mass on T1-weighted MRI and hyperintense mass on T2-weighted MRI.<ref name="radio">  Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015</ref>


==MRI==
==MRI==

Revision as of 13:32, 19 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [3]

Overview

On head and neck MRI, retinoblastoma is characterized by isointense to hypointense mass on T1-weighted MRI and hyperintense mass on T2-weighted MRI.[1]

MRI

MRI is the modality of choice for pre-treatment staging on retinoblastoma.

  • The MRI features of retinoblastoma include:[1]
MRI component Features
T1
  • Intermediate signal intensity, hyperintense c.f. vitreous
T2
  • Hypointense c.f. vitreous
T1 contrast with gadolinium
  • The mass usually enhances relatively homogeneously when small
  • Larger tumours often have areas of necrosis, rendering it heterogeneous
  • Linear enhancement of the choroid beyond the margins of the tumour should raise the possibility of choroidal involvement, although inflammation may lead to similar appearance
  • Enhancement of the anterior chamber need not represent tumour involvement, with hyperaemia, uveitis and iris neovascularisation all leading to asymmetric enhancement
  • Careful assessment of the optic disc and optic nerve should be carried out to assess for involvement
  • Extra-ocular extension through the sclera will be visible as interruption of the otherwise hypointense non-enhancing sclera by enhancing tumour
Diffusion Weighted Imaging
  • The tumour shows restricted diffusion on DWI at high b values. It exhibits low ADC values in contrast to the high intensity of the vitreous in the ADC maps
  • ADC map can be used to differentiate viable and necrotic tumour
  • DWI is valuable in evaluating the response to eye-preservation treatment
Axial MRI showing retinoblastoma[2]
T1 MRI showing retinoblastoma[2]
T2 MRI showing retinoblastoma[2]

References

  1. 1.0 1.1 Retinoblastoma. Radiopedia(2015) http://radiopaedia.org/articles/retinoblastoma Accessed on October 10, 2015
  2. 2.0 2.1 2.2 Image courtesy of Radswiki Radiopaedia (original file [1]).[http://radiopaedia.org/licence Creative Commons BY-SA-NC

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