Pancreatic fistula laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
[[Pleural]] or [[ascitic]] fluid should be sent for analysis. An elevated [[amylase]] level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. [[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. | [[Pleural]] or [[ascitic]] fluid should be sent for analysis. An elevated [[amylase]] level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. [[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
*Fluid samples collected via [[thoracentesis]], [[paracentesis]] or fluid collected via [[percutaneous]] drainage from an external [[fistula]] can be analyzed for [[amylase]] level, which helps solidify the diagnosis of [[pancreatic cancer]]. | *Fluid samples collected via [[thoracentesis]], [[paracentesis]] or fluid collected via [[percutaneous]] drainage from an external [[fistula]] can be analyzed for [[amylase]] level, which helps solidify the diagnosis of [[pancreatic cancer]]. | ||
*[[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. | |||
* [[Complete blood count]] is necessary to check for any ongoing [[infection]] or [[hemorrhage]]. Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. | *Complete metabolic panel including [[inflammatory]] markers, [[Electrolyte|serum electrolytes]], [[liver function tests]], [[calcium]], [[albumin]], [[amylase]] and [[lipase]] should be sent to [[laboratory]] for evaluation. | ||
*Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. [[Pancreatic]] fluid [[amylase]] level will be >1000 u/dl.<ref name="pmid24650171">{{cite journal| author=Larsen M, Kozarek R| title=Management of pancreatic ductal leaks and fistulae. | journal=J Gastroenterol Hepatol | year= 2014 | volume= 29 | issue= 7 | pages= 1360-70 | pmid=24650171 | doi=10.1111/jgh.12574 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24650171 }} </ref><ref name="pmid18053844">{{cite journal| author=Morgan KA, Adams DB| title=Management of internal and external pancreatic fistulas. | journal=Surg Clin North Am | year= 2007 | volume= 87 | issue= 6 | pages= 1503-13, x | pmid=18053844 | doi=10.1016/j.suc.2007.08.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18053844 }} </ref> | |||
* Furthermore, [[pancreatic]] [[fistula]] leak presenting as [[ascites]] or [[pleural effusion]] should be analyzed for fluid [[protein]], [[albumin]], [[lactate dehydrogenase]], [[glucose]], gram cultures and total cell count. [[Pancreatic]] fluid [[amylase]] level will be >1000 u/dl.<ref name="pmid24650171">{{cite journal| author=Larsen M, Kozarek R| title=Management of pancreatic ductal leaks and fistulae. | journal=J Gastroenterol Hepatol | year= 2014 | volume= 29 | issue= 7 | pages= 1360-70 | pmid=24650171 | doi=10.1111/jgh.12574 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24650171 }} </ref><ref name="pmid18053844">{{cite journal| author=Morgan KA, Adams DB| title=Management of internal and external pancreatic fistulas. | journal=Surg Clin North Am | year= 2007 | volume= 87 | issue= 6 | pages= 1503-13, x | pmid=18053844 | doi=10.1016/j.suc.2007.08.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18053844 }} </ref> | *[[Pleural]] or [[ascitic]] fluid should be sent for analysis. An elevated [[amylase]] level, usually > 1,000 IU/L, with [[protein]] levels over 3.0 g/dL is diagnostic. | ||
* [[Pleural]] or [[ascitic]] fluid should be sent for analysis. An elevated [[amylase]] level, usually > 1,000 IU/L, with [[protein]] levels over 3.0 g/dL is diagnostic. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 14:03, 13 April 2021
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Pancreatic fistula Microchapters |
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Pancreatic fistula laboratory findings On the Web |
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American Roentgen Ray Society Images of Pancreatic fistula laboratory findings |
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Risk calculators and risk factors for Pancreatic fistula laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pleural or ascitic fluid should be sent for analysis. An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic. Complete blood count is necessary to check for any ongoing infection or hemorrhage. Complete metabolic panel including inflammatory markers, serum electrolytes, liver function tests, calcium, albumin, amylase and lipase should be sent to laboratory for evaluation. Furthermore, pancreatic fistula leak presenting as ascites or pleural effusion should be analyzed for fluid protein, albumin, lactate dehydrogenase, glucose, gram cultures and total cell count.
Laboratory Findings
- Fluid samples collected via thoracentesis, paracentesis or fluid collected via percutaneous drainage from an external fistula can be analyzed for amylase level, which helps solidify the diagnosis of pancreatic cancer.
- Complete blood count is necessary to check for any ongoing infection or hemorrhage.
- Complete metabolic panel including inflammatory markers, serum electrolytes, liver function tests, calcium, albumin, amylase and lipase should be sent to laboratory for evaluation.
- Furthermore, pancreatic fistula leak presenting as ascites or pleural effusion should be analyzed for fluid protein, albumin, lactate dehydrogenase, glucose, gram cultures and total cell count. Pancreatic fluid amylase level will be >1000 u/dl.[1][2]
- Pleural or ascitic fluid should be sent for analysis. An elevated amylase level, usually > 1,000 IU/L, with protein levels over 3.0 g/dL is diagnostic.
References
- ↑ Larsen M, Kozarek R (2014). "Management of pancreatic ductal leaks and fistulae". J Gastroenterol Hepatol. 29 (7): 1360–70. doi:10.1111/jgh.12574. PMID 24650171.
- ↑ Morgan KA, Adams DB (2007). "Management of internal and external pancreatic fistulas". Surg Clin North Am. 87 (6): 1503–13, x. doi:10.1016/j.suc.2007.08.008. PMID 18053844.