Nedocromil

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Nedocromil
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Clinical data
Routes of
administration
Inhalation and eye drops
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
Pharmacokinetic data
Protein binding89%
Metabolismnot metabolized
Elimination half-life~3.3 hours
Excretionexcreted unchanged
Identifiers
CAS Number
PubChem CID
DrugBank
E number{{#property:P628}}
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Chemical and physical data
FormulaC19H17NO7
Molar mass371.341 g/mol

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Overview

Nedocromil sodium is a medication used to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. It is administered by an inhaler under the brand name Tilade.

Nedocromil is classified as a cromone. Nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes.


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