Necrotizing fasciitis overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]
Overview
Necrotizing fasciitis or fasciitis necroticans, commonly known as “flesh-eating bacteria,” is a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue. Many types of bacteria can cause necrotizing fasciitis (eg. Group A streptococcus, Vibrio vulnificus, Clostridium perfringens, Bacteroides fragilis), of which Group A streptococcus (also known as Streptococcus pyogenes) is the most common cause. It is severe inflammation of the muscle sheath that leads to necrosis of subcutaneous tissue and adjacent fascia.[1]
Historical Perspective
Necrotizing fasciitis was first described by Hippocrates in the fifth century B.C. as the complication of erysipelas.[2][3]It was described as "hospital gangrene" by confederate army surgeon Joseph jones.[4][5]Meleney reported a series of 20 patients in 1924 as having hemolytic streptococcal gangrene, later called Meleney's gangrene.[6]Necrotizing fasciitis of perineum was described in 1883 by the French physician, Jean Alfred Fournier.[7]
Classification
Necrotizing fasciitis may be classified according to international classification of diseases-10 (ICD-10) into M72.6 Necrotizing fasciitis.[8]Based on microbiological findings, necrotizing fasciitis may be classified into four types (type I, type II, type III, type IV). Necrotizing fasciitis is further classified based on anatomic location and severity of symptoms.[9]
Pathophysiology
Causes
Differentiating Necrotizing fasciitis overview from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
References
- ↑ Misiakos EP, Bagias G, Patapis P, Sotiropoulos D, Kanavidis P, Machairas A (2014). "Current concepts in the management of necrotizing fasciitis". Front Surg. 1: 36. doi:10.3389/fsurg.2014.00036. PMC 4286984. PMID 25593960.
- ↑ Descamps V, Aitken J, Lee MG (1994). "Hippocrates on necrotising fasciitis". Lancet. 344 (8921): 556. PMID 7914656.
- ↑ Hasham S, Matteucci P, Stanley PR, Hart NB (2005). "Necrotising fasciitis". BMJ. 330 (7495): 830–3. doi:10.1136/bmj.330.7495.830. PMC 556077. PMID 15817551.
- ↑ WILSON B (1952). "Necrotizing fasciitis". Am Surg. 18 (4): 416–31. PMID 14915014.
- ↑ Janevicius RV, Hann SE, Batt MD (1982). "Necrotizing fasciitis". Surg Gynecol Obstet. 154 (1): 97–102. PMID 7031943.
- ↑ Sadasivan J, Maroju NK, Balasubramaniam A (2013). "Necrotizing fasciitis". Indian J Plast Surg. 46 (3): 472–8. doi:10.4103/0970-0358.121978. PMC 3897089. PMID 24459334.
- ↑ Chennamsetty A, Khourdaji I, Burks F, Killinger KA (2015). "Corary diagnosis and management of Fournier's gangrene". Ther Adv Urol. 7 (4): 203–15. doi:10.1177/1756287215584740. PMC 4580094. PMID 26445600.
- ↑ ICD-10 version:2016. http://apps.who.int/classifications/icd10/browse/2016/en#/M72.6 2016 Accessed on August 25,2016
- ↑ Lancerotto L, Tocco I, Salmaso R, Vindigni V, Bassetto F (2012). "Necrotizing fasciitis: classification, diagnosis, and management". J Trauma Acute Care Surg. 72 (3): 560–6. doi:10.1097/TA.0b013e318232a6b3. PMID 22491537.