Myocarditis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S.
Natural history
Majority of myocarditis with myocardial infarction like ECG changes are usually self limiting with no overt sequelae[1]. Patients with ECG changes suggestive of bundle branch block, old infarct or high degree AV block are associated with poor long term prognosis and may progress to develop cardiac failure. Viral myocarditis are usually benign and majority of cases of Coxsackie B virus infection are subclinical.
Patients presenting with mild ventricular dysfunction secondary to viral myocarditis typically improve within weeks to months and rarely, may progress to severe ventricular dysfunction and may lead to arrhythmias or even death[2]. Though only a small fraction of patients with lymphocytic myocarditis develop ventricular arrhythmias, idiopathic ventricular arrhythmias is seen in upto 33% of these patients[3].
References
- ↑ Dec GW, Waldman H, Southern J, Fallon JT, Hutter AM, Palacios I (1992). "Viral myocarditis mimicking acute myocardial infarction". J Am Coll Cardiol. 20 (1): 85–9. PMID 1607543.
- ↑ Wentworth P, Jentz LA, Croal AE (1979). "Analysis of sudden unexpected death in southern Ontario, with emphasis on myocarditis". Can Med Assoc J. 120 (6): 676–80, 706. PMC 1819176. PMID 436050.
- ↑ Hosenpud JD, McAnulty JH, Niles NR (1986). "Unexpected myocardial disease in patients with life threatening arrhythmias". Br Heart J. 56 (1): 55–61. PMC 1277385. PMID 3730208.