Multiple endocrine neoplasia type 1 physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Common physical examination findings of multiple endocrine neoplasia type 1 include rash, lymphadenopathy, fever and abdominal mass.

Physical Examination

Appearance of the Patient

• The general appearance of patients with multiple endocrine neoplasia type 1 range from normal appearance to obese, thin, and cachectic. Patient appearance largely depends on the manifestations of the syndrome.

Vitals

• A fever is often present
• Tachycardia may be present
• The pulse is regular
• Tachypnea may be present

Skin

• Skin eruption of red patches with irregular borders, intact and ruptured vesicles, and crust formation

Eyes

• Nystagmus may be present
• Extra-ocular movements may be abnormal

Ears

• Hearing acuity may be reduced
• Weber test
• Rinne test

Neck

• Jugular venous pressure may be elevated
• Lymphadenopathy

Abdomen

• Abdominal tenderness may be present
• An abdominal mass may be present

Extremities

• Edema may be present

Neurologic

• Mental status may be altered
• Clonus may be present