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==Overview==
==Overview==
Biopsy for lung mass may be classified into 2 categories: non-surgical biopsy and surgical biopsy. Biopsy findings associated with lung mass will depend on tumor [[histology]]. Common types of lung tissue biopsy for pulmonary mass, include: conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass, include: suspected lung cancer, malignant features (lymph node involvement).<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
[[Biopsy]] for lung mass may be classified into 2 categories such as non-surgical biopsy and surgical biopsy. [[Biopsy]] findings associated with lung mass will depend on tumor [[histology]]. Common types of lung tissue [[biopsy]] for pulmonary mass, include conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle [[aspiration]], endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass include; suspected [[lung cancer]], [[malignant]] features ([[lymph node]] involvement).


==Other Diagnostic Studies==
==Other Diagnostic Studies==
===Biopsy===
===Biopsy===
Biopsy for lung mass may be classified into 2 categories:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
Biopsy for lung mass may be classified into 2 categories:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Bronchoscopy
:*[[Bronchoscopy]]
:*Transthoracic needle biopsy
:*Transthoracic [[needle biopsy]]
:*Needle core biopsy  
:*Needle core biopsy  
*'''Surgical'''
*'''Surgical'''
:* Wedge resection
:* [[Wedge resection (lung)|Wedge resection]]
* The preferred biopsy technique for lung mass is wedge resection.
* The preferred [[biopsy]] technique for lung mass is [[Wedge resection (lung)|wedge resection.]]


*Indications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
*Indications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Suspected lung cancer
:*Suspected [[lung cancer]]
:*Determination of tumor histologic subtype  
:*Determination of tumor [[histologic]] subtype  
:*Characterization of genetic mutations
:*Characterization of [[genetic]] [[mutations]]


*Contraindications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
*Contraindications for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Emphysema
:*[[Emphysema]]
:*Bullous disease
:*[[Bullous]] disease
:*Chronic respiratory failure
:*Chronic respiratory failure


*Complications for for biopsy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>  
*Complications for [[biopsy]] in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>  
:*Pneumothorax
:*[[Pneumothorax]]
:*Hemothorax
:*[[Hemothorax]]
==Non-Surgical Biopsy==
==Non-Surgical Biopsy==


'''Bronchoscopy'''
'''Bronchoscopy'''


*Common bronchoscopy biopsy techniques for lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
*Common [[bronchoscopy]] [[biopsy]] techniques for lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Conventional bronchoscopic-guided transbronchial biopsy  
:*Conventional bronchoscopic-guided transbronchial biopsy  
:*Bronchoscopic-transbronchial needle aspiration  
:*Bronchoscopic-transbronchial needle aspiration  
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:*Endobronchial ultrasound-guided transbronchial needle aspiration  
:*Endobronchial ultrasound-guided transbronchial needle aspiration  


*Indications for bronchoscopy in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
*Indications for [[bronchoscopy]] in lung mass, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Central nodules  
:*Central [[nodules]]
:*Large lesions
:*Large lesions
:*No fitness for surgery  
:*No fitness for surgery  
:*Nodules close to the patent airways  
:*[[Nodules]] close to the patent airways  
:*Patients were the risk of complications from any other biopsy is high
:*Patients were the risk of complications from any other [[biopsy]] is high


'''Transthoracic needle biopsy'''
'''Transthoracic needle biopsy'''
*Usually followed by CT guidance
*Usually followed by [[CT]] guidance
*Indications for transthoracic needle biopsy in pulmonary nodule, include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
*Indications for transthoracic [[needle biopsy]] in pulmonary mass include:<ref name="pmid15347106">{{cite journal |vauthors=Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM |title=Percutaneous biopsy in evaluation of lung nodules |journal=JSLS |volume=8 |issue=3 |pages=213–6 |year=2004 |pmid=15347106 |pmc=3016799 |doi= |url=}}</ref>
:*Peripheral nodules  
:*Peripheral [[nodules]]
:*Nodules close to the chest wall
:*Nodules close to the [[chest wall]]
:*No fitness for surgery  
:*No fitness for [[surgery]]


==Surgical Biopsy==
==Surgical Biopsy==
*Surgical excision is the mainstay therapy for malignant lung mass.
*Surgical [[excision]] is the mainstay therapy for malignant lung mass.
*Surgical excision is also the primary choice for the definitive diagnosis of malignant lung mass.
*Surgical [[excision]] is also the primary choice for the definitive [[diagnosis]] of [[malignant]] lung mass.
*In lung mass, surgical procedure selection will depend on the size, margins, and size of the tumor.
*In lung mass, surgical procedure selection will depend on the size, margins, and size of the [[tumor]].
*Common surgical procedures for the treatment of lung mass, include:  
*Common surgical procedures for the treatment of lung mass, include:  
:*Wedge resection  
:*[[Wedge resection (lung)|Wedge resection]]
:*Lobectomy  
:*[[Lobectomy of lung|Lobectomy]]
:*Segmentectomy  
:*Segmentectomy  
:*Lung volume reduction surgery
:*Lung volume reduction surgery

Revision as of 16:02, 9 March 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Akshun Kalia M.B.B.S.[3]

Overview

Biopsy for lung mass may be classified into 2 categories such as non-surgical biopsy and surgical biopsy. Biopsy findings associated with lung mass will depend on tumor histology. Common types of lung tissue biopsy for pulmonary mass, include conventional bronchoscopic-guided transbronchial biopsy, bronchoscopic-transbronchial needle aspiration, endobronchial ultrasound-guided sheath transbronchial biopsy, and endobronchial ultrasound-guided transbronchial needle aspiration. Common indications for biopsy in lung mass include; suspected lung cancer, malignant features (lymph node involvement).

Other Diagnostic Studies

Biopsy

Biopsy for lung mass may be classified into 2 categories:[1]

  • Surgical
  • Indications for biopsy in lung mass, include:[1]
  • Contraindications for biopsy in lung mass, include:[1]
  • Complications for biopsy in lung mass, include:[1]

Non-Surgical Biopsy

Bronchoscopy

  • Conventional bronchoscopic-guided transbronchial biopsy
  • Bronchoscopic-transbronchial needle aspiration
  • Endobronchial ultrasound-guided sheath transbronchial biopsy
  • Endobronchial ultrasound-guided transbronchial needle aspiration
  • Central nodules
  • Large lesions
  • No fitness for surgery
  • Nodules close to the patent airways
  • Patients were the risk of complications from any other biopsy is high

Transthoracic needle biopsy

  • Usually followed by CT guidance
  • Indications for transthoracic needle biopsy in pulmonary mass include:[1]

Surgical Biopsy

  • Surgical excision is the mainstay therapy for malignant lung mass.
  • Surgical excision is also the primary choice for the definitive diagnosis of malignant lung mass.
  • In lung mass, surgical procedure selection will depend on the size, margins, and size of the tumor.
  • Common surgical procedures for the treatment of lung mass, include:

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Podbielski FJ, Rodriguez HE, Brown AM, Blecha MJ, Salazar MR, Connolly MM (2004). "Percutaneous biopsy in evaluation of lung nodules". JSLS. 8 (3): 213–6. PMC 3016799. PMID 15347106.