Lung mass history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The hallmark symptoms of lung mass, include: [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]], [[Asbestosis|exposure to asbestos]], [[tuberculosis infection]], or a [[Occupational safety and health|high risk occupation]] may be suggestive of a lung mass. Symptoms related with lung mass will vary depending | The hallmark symptoms of lung mass, include: [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]], [[Asbestosis|exposure to asbestos]], [[tuberculosis infection]], or a [[Occupational safety and health|high risk occupation]] may be suggestive of a lung mass. Symptoms related with lung mass will vary depending upon the size and location of tumor. Common symptoms of lung mass may also include [[shortness of breath]], [[fatigue]], and [[chest pain]].<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref> | ||
==History== | ==History== | ||
*Obtaining the history is an important aspect of making the diagnosis of lung mass. Complete history will help determine the likelihood of malignancy, and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref> | *Obtaining the [[History and Physical examination|history]] is an important aspect of making the [[Diagnosis-related group|diagnosis]] of lung mass. Complete history will help determine the likelihood of [[malignancy]], and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref> | ||
:*Age | :*[[Age]] | ||
:*Family history of cancer | :*Family history of [[cancer]] | ||
:*Personal history of cancer | :*Personal history of [[cancer]] | ||
:*Positive history of active/passive smoking | :*Positive history of active/[[passive smoking]] | ||
::*Number of cigarettes/year | ::*Number of cigarettes/year | ||
::*Number of years/months of active smoking | ::*Number of years/months of active smoking | ||
| Line 22: | Line 22: | ||
::*Chronic (> 6 weeks) | ::*Chronic (> 6 weeks) | ||
:*Previous or current lung disease, such as: | :*Previous or current lung disease, such as: | ||
::*Chronic obstructive pulmonary disease | ::*[[Chronic obstructive pulmonary disease]] | ||
::*Interstitial lung disease | ::*[[Interstitial lung disease]] | ||
*Several patient factors may influence the likelihood of a benign versus a malignant condition | *Several patient factors may influence the likelihood of a [[benign]] versus a [[malignant]] condition; these include previous exposure to smoke or other [[carcinogen]]s such as [[asbestos]], and previously diagnosed cancer or [[respiratory infection]]s. A patient with airway symptoms, especially [[hemoptysis]], is more likely to have [[cancer]] compared to a patient with no respiratory symptoms. | ||
==Common Symptoms== | ==Common Symptoms== | ||
*The majority of lung masses are [[asymptomatic]] and are usually found incidentally.<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref> | *The majority of lung masses are [[asymptomatic]] and are usually found incidentally.<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref> | ||
* | |||
=== Common symptoms === | |||
*Chronic [[cough]] | |||
*[[Weight loss]] | |||
*[[Hemoptysis]] | |||
*Other symptoms that suggest lung mass, include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref> | *Other symptoms that suggest lung mass, include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref> | ||
:* [[Dyspnea]] | :* [[Dyspnea]] | ||
:* [[Wheezing]] | |||
:* [[Wheezing]] | |||
:* [[Chest pain]] | :* [[Chest pain]] | ||
:* [[Abdominal pain]] | :* [[Abdominal pain]] | ||
| Line 42: | Line 44: | ||
==Prognosis== | ==Prognosis== | ||
*Patients with lung adenocarcinomas from EGFR mutations have a more favourable prognosis when treated with tyrosine kinase inhibitors | *Patients with lung [[adenocarcinomas]] from [[EGFR]] mutations have a more favourable [[prognosis]] when treated with chemotherapy ([[tyrosine kinase inhibitors]] or TKIs). | ||
*The use of TKIs have been observed with significantly longer remission and higher survival rates as compared to patients lacking mutation in EGFR. | *The use of TKIs have been observed with significantly longer [[remission]] and higher survival rates as compared to patients lacking [[mutation]] in [[EGFR]]. | ||
==References== | ==References== | ||
Revision as of 15:31, 9 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
The hallmark symptoms of lung mass, include: chronic cough, weight loss, and hemoptysis. A positive history of smoking, exposure to asbestos, tuberculosis infection, or a high risk occupation may be suggestive of a lung mass. Symptoms related with lung mass will vary depending upon the size and location of tumor. Common symptoms of lung mass may also include shortness of breath, fatigue, and chest pain.[1][2]
History
- Obtaining the history is an important aspect of making the diagnosis of lung mass. Complete history will help determine the likelihood of malignancy, and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:[3]
- Age
- Family history of cancer
- Personal history of cancer
- Positive history of active/passive smoking
- Number of cigarettes/year
- Number of years/months of active smoking
- Number of years/months of second-hand smoking
- Number of years/months of smoking cessation
- Previous primary infection of tuberculosis
- Onset of pulmonary symptoms
- Acute (< 6 weeks)
- Chronic (> 6 weeks)
- Previous or current lung disease, such as:
- Several patient factors may influence the likelihood of a benign versus a malignant condition; these include previous exposure to smoke or other carcinogens such as asbestos, and previously diagnosed cancer or respiratory infections. A patient with airway symptoms, especially hemoptysis, is more likely to have cancer compared to a patient with no respiratory symptoms.
Common Symptoms
- The majority of lung masses are asymptomatic and are usually found incidentally.[1]
Common symptoms
- Chronic cough
- Weight loss
- Hemoptysis
- Other symptoms that suggest lung mass, include:[4][5]
Prognosis
- Patients with lung adenocarcinomas from EGFR mutations have a more favourable prognosis when treated with chemotherapy (tyrosine kinase inhibitors or TKIs).
- The use of TKIs have been observed with significantly longer remission and higher survival rates as compared to patients lacking mutation in EGFR.
References
- ↑ 1.0 1.1 Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016
- ↑ Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I non-small cell lung cancer: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
- ↑ Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
- ↑ Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=ignored (help) - ↑ Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015