Adenocarcinoma
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Adenocarcinoma is a form of carcinoma that originates in glandular tissue. To be classified as adenocarcinoma, the cells do not necessarily need to be part of a gland, as long as they have secretory properties. This form of carcinoma can occur in some higher mammals, including humans.[1] The term adenocarcinoma is derived from 'adeno' meaning 'pertaining to a gland' and 'carcinoma', which describes a cancer that has developed in the epithelial cells. It can first present as an adenoma (a glandular tumor that is benign).
Pathophysiology
Examples of tissues where adenocarcinomas may arise:
- Breast cancer
- Colon cancer
- Lung cancer
- Prostate cancer
- Stomach cancer
- Pancreatic cancer (99% of pancreatic cancers are ductal adenocarcinomas [2])
- Cervical cancer
- Vaginal cancer
Physical Examination
Adenocarcinoma-In The Submandibular Salivary Glands
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Adenocarcinoma-In The Submandibular Salivary Glands
Adapted from Dermatology Atlas -
Adenocarcinoma-In The Submandibular Salivary Glands
Adapted from Dermatology Atlas -
Adenocarcinoma-In The Submandibular Salivary Glands
Adapted from Dermatology Atlas
Differential Diagnosis
Diseases | Risk factors/Epidemiology | History | Clinical Findings | Gross Pathology | Histopathology | Immunohistochemistry | Lab Findings | Imaging | Metastatic Potential | Gold Standard | Additional Findings |
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Head & Neck Cancer | |||||||||||
Paranasal Sinus Cancer | |||||||||||
Lung Cancer | |||||||||||
Breast Cancer | |||||||||||
Esophageal Cancer | |||||||||||
Diseases | Risk factors/Epidemiology | History | Clinical Findings | Gross Pathology | Histopathology | Immunohistochemistry | Lab Findings | Imaging | Metastatic Potential | Gold Standard | Additional Findings |
Gastric Cancer | |||||||||||
Pancreatic Cancer | |||||||||||
Small Bowel Cancer | |||||||||||
Colorectal Cancer | |||||||||||
Appendix Cancer | |||||||||||
Diseases | Risk factors/Epidemiology | History | Clinical Findings | Gross Pathology | Histopathology | Immunohistochemistry | Lab Findings | Imaging | Metastatic Potential | Gold Standard | Additional Findings |
Gallbladder Cancer | |||||||||||
Anal Cancer | |||||||||||
Cervical Cancer | |||||||||||
Vaginal Cancer | |||||||||||
Endometrial Cancer | |||||||||||
Vulvar Cancer | |||||||||||
Diseases | Risk factors/Epidemiology | History | Clinical Findings | Gross Pathology | Histopathology | Immunohistochemistry | Lab Findings | Imaging | Metastatic Potential | Gold Standard | Additional Findings |
Prostate Cancer | |||||||||||
Testicular Cancer | |||||||||||
Urinary Bladder Cancer | |||||||||||
Urethral Cancer | |||||||||||
Metastatic Cancer | |||||||||||
Cancer of Unknown Primary |
References
- ↑ Fauquier, D.A., Gulland, F.M.D.,(Marine Mammal Center), Haulena, M., Spraker, T., ‘’Biliary adenocarcinoma in a stranded Northern elephant seal (‘’Mirounga angustirortsis’‘)’‘, Journal of Wildlife Diseases 39(3):723-726 (2003)