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{{Loefflers syndrome }}
{{Loefflers syndrome }}
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==Overview==
==Overview==
The majority of patients with Löffler syndrome generally presents as a mild syndrome which spontaneously resolves after 2-4 weeks. The symptoms of Löffler syndrome usually develop 10-16 days after ingestion of ''[[Ascaris lumbricoides|Ascaris]]'' eggs, or ''[[Necator americanus|N americanus,]] A duodenale,'' ''S stercoralis'' infection, and start with common symptoms such as fever, malaise, cough, wheezing, and dyspnea. Cough is the most common symptom, which is generally dry and nonproductive but might be productive or even present with small amounts of blood-tinged mucoid sputum. Less common symptoms of Löffler syndrome include myalgia, anorexia, and urticaria. In order to identify risk factors for exposure to parasites, immigration status, socioeconomic status, hygiene, sanitation, as well as travel history should be carefully elicited.
==History and Symptoms==
==History and Symptoms==
*The majority of patients with Löffler syndrome generally presents as a mild syndrome which spontaneously resolves after 2-4 weeks.<ref name="pmid24931460">Ekin S, Sertogullarindan B, Gunbatar H, Arisoy A, Yildiz H (2016) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=24931460 Loeffler's syndrome: an interesting case report.] ''Clin Respir J'' 10 (1):112-4. [http://dx.doi.org/10.1111/crj.12173 DOI:10.1111/crj.12173] PMID: [https://pubmed.gov/24931460 24931460]</ref>
*.The symptoms of Löffler syndrome usually develop 10-16 days after ingestion of ''Ascaris'' eggs, or ''N americanus, A duodenale,'' ''S stercoralis'' infection, and start with common symptoms such as fever, malaise, cough, wheezing, and dyspnea.<ref name="pmid5667987"> (1968) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=5667987 Löffler's syndrome.] ''Br Med J'' 3 (5618):569-70. PMID: [https://pubmed.gov/5667987 5667987]</ref> 
===History===
In order to identify risk factors for exposure to parasites, immigration status, socioeconomic status, hygiene, sanitation, as well as travel history should be carefully elicited.
Patients with [disease name]] may have a positive history of:
*Travel to the endemic areas of parasites like humid tropical countries
*Immigration from the underdeveloped countries
*Low socioeconomic status
*living in an area with limited sanitation and irrigation
*Camping and other recreational activities
===Common Symptoms===
Cough is the most common symptom, which is generally dry and nonproductive but might be productive or even present with small amounts of blood-tinged mucoid sputum.<ref name="pmid5667987"> (1968) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=5667987 Löffler's syndrome.] ''Br Med J'' 3 (5618):569-70. PMID: [https://pubmed.gov/5667987 5667987]</ref> 
* [[Chest pain]]
* [[Chest pain]]
* [[Dry cough]]
* [[Dry cough]]
Line 13: Line 30:
* [[Wheezing]]
* [[Wheezing]]


Symptomatic patients most often complain of an irritating, nonproductive cough and burning substernal discomfort that is aggravated by coughing or deep breathing. Dyspnea, wheezing, fever, and blood-tinged sputum containing eosinophil-derived Charcot-Leyden crystals may also be present.<ref name="pmid21062596">Te Booij M, de Jong E, Bovenschen HJ (2010) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=21062596 Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature.] ''Dermatol Online J'' 16 (10):2. PMID: [https://pubmed.gov/21062596 21062596]</ref><ref name="pmid16612768">Chitkara RK, Krishna G (2006) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16612768 Parasitic pulmonary eosinophilia.] ''Semin Respir Crit Care Med'' 27 (2):171-84. [http://dx.doi.org/10.1055/s-2006-939520 DOI:10.1055/s-2006-939520] PMID: [https://pubmed.gov/16612768 16612768]</ref>
===Less Common Symptoms===
Less common symptoms of Löffler syndrome include:<ref name="pmid21062596">Te Booij M, de Jong E, Bovenschen HJ (2010) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=21062596 Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature.] ''Dermatol Online J'' 16 (10):2. PMID: [https://pubmed.gov/21062596 21062596]</ref><ref name="pmid14819567">HEIKEN CA, WIESE ER (1951) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=14819567 Löffler's syndrome; transient pulmonary infiltration with eosinophilia.] ''Am Rev Tuberc'' 63 (4):480-6. PMID: [https://pubmed.gov/14819567 14819567]</ref>
*Myalgia
*Anorexia,
*Urticaria
{{#ev:youtube|UAf1QGc0MmY}}
==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}


[[Category:Pulmonology]]
[[Category:Pulmonology]]

Latest revision as of 20:32, 31 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]

Overview

The majority of patients with Löffler syndrome generally presents as a mild syndrome which spontaneously resolves after 2-4 weeks. The symptoms of Löffler syndrome usually develop 10-16 days after ingestion of Ascaris eggs, or N americanus, A duodenale, S stercoralis infection, and start with common symptoms such as fever, malaise, cough, wheezing, and dyspnea. Cough is the most common symptom, which is generally dry and nonproductive but might be productive or even present with small amounts of blood-tinged mucoid sputum. Less common symptoms of Löffler syndrome include myalgia, anorexia, and urticaria. In order to identify risk factors for exposure to parasites, immigration status, socioeconomic status, hygiene, sanitation, as well as travel history should be carefully elicited.

History and Symptoms

  • The majority of patients with Löffler syndrome generally presents as a mild syndrome which spontaneously resolves after 2-4 weeks.[1]
  • .The symptoms of Löffler syndrome usually develop 10-16 days after ingestion of Ascaris eggs, or N americanus, A duodenale, S stercoralis infection, and start with common symptoms such as fever, malaise, cough, wheezing, and dyspnea.[2]

History

In order to identify risk factors for exposure to parasites, immigration status, socioeconomic status, hygiene, sanitation, as well as travel history should be carefully elicited.

Patients with [disease name]] may have a positive history of:

  • Travel to the endemic areas of parasites like humid tropical countries
  • Immigration from the underdeveloped countries
  • Low socioeconomic status
  • living in an area with limited sanitation and irrigation
  • Camping and other recreational activities

Common Symptoms

Cough is the most common symptom, which is generally dry and nonproductive but might be productive or even present with small amounts of blood-tinged mucoid sputum.[2]

Symptomatic patients most often complain of an irritating, nonproductive cough and burning substernal discomfort that is aggravated by coughing or deep breathing. Dyspnea, wheezing, fever, and blood-tinged sputum containing eosinophil-derived Charcot-Leyden crystals may also be present.[3][4]

Less Common Symptoms

Less common symptoms of Löffler syndrome include:[3][5]

  • Myalgia
  • Anorexia,
  • Urticaria


{{#ev:youtube|UAf1QGc0MmY}}

References

  1. Ekin S, Sertogullarindan B, Gunbatar H, Arisoy A, Yildiz H (2016) Loeffler's syndrome: an interesting case report. Clin Respir J 10 (1):112-4. DOI:10.1111/crj.12173 PMID: 24931460
  2. 2.0 2.1 (1968) Löffler's syndrome. Br Med J 3 (5618):569-70. PMID: 5667987
  3. 3.0 3.1 Te Booij M, de Jong E, Bovenschen HJ (2010) Löffler syndrome caused by extensive cutaneous larva migrans: a case report and review of the literature. Dermatol Online J 16 (10):2. PMID: 21062596
  4. Chitkara RK, Krishna G (2006) Parasitic pulmonary eosinophilia. Semin Respir Crit Care Med 27 (2):171-84. DOI:10.1055/s-2006-939520 PMID: 16612768
  5. HEIKEN CA, WIESE ER (1951) Löffler's syndrome; transient pulmonary infiltration with eosinophilia. Am Rev Tuberc 63 (4):480-6. PMID: 14819567

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