Langerhans cell histiocytosis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Common risk factors in the development of Langerhans cell histiocytosis are cigarette smoking and family history.

Risk Factors

Common risk factors in the development of Langerhans cell histiocytosis are:[1][2][3]

  • Cigarette smoking
  • Family history
  • Maternal urinary tract infection during the index pregnancy
  • Feeding problems during infancy
  • Blood transfusions during infancy

References

  1. Langerhans cell histiocytosis. Libre Pathology (2015) http://librepathology.org/wiki/index.php/Langerhans_cell_histiocytosis#cite_note-10 Accessed on February, 3 2016
  2. Hamre M, Hedberg J, Buckley J, Bhatia S, Finlay J, Meadows A, Nesbit M, Smithson A, Robison L (February 1997). "Langerhans cell histiocytosis: an exploratory epidemiologic study of 177 cases". Med. Pediatr. Oncol. 28 (2): 92–7. PMID 8986144.
  3. Satter EK, High WA (2008). "Langerhans cell histiocytosis: a review of the current recommendations of the Histiocyte Society". Pediatr Dermatol. 25 (3): 291–5. doi:10.1111/j.1525-1470.2008.00669.x. PMID 18577030.


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