KLF13

Kruppel-like factor 13
Identifiers
Symbols	KLF13 ; BTEB3; FKLF2; NSLP1; RFLAT-1; RFLAT1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 32288
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE KLF13 219878 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Kruppel-like factor 13, also known as KLF13, is a human gene.

KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000).[supplied by OMIM]

See also

• Kruppel-like factors

Further reading

• Cook T, Gebelein B, Urrutia R (1999). "Sp1 and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors". Ann. N. Y. Acad. Sci. 880: 94–102. PMID 10415854.CS1 maint: Multiple names: authors list (link)
• Song A, Chen YF, Thamatrakoln K; et al. (1999). "RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes". Immunity. 10 (1): 93–103. PMID 10023774.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Asano H, Li XS, Stamatoyannopoulos G (2000). "FKLF-2: a novel Krüppel-like transcriptional factor that activates globin and other erythroid lineage genes". Blood. 95 (11): 3578–84. PMID 10828046.CS1 maint: Multiple names: authors list (link)
• Scohy S, Gabant P, Van Reeth T; et al. (2001). "Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family". Genomics. 70 (1): 93–101. doi:10.1006/geno.2000.6362. PMID 11087666.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kaczynski J, Zhang JS, Ellenrieder V; et al. (2001). "The Sp1-like protein BTEB3 inhibits transcription via the basic transcription element box by interacting with mSin3A and HDAC-1 co-repressors and competing with Sp1". J. Biol. Chem. 276 (39): 36749–56. doi:10.1074/jbc.M105831200. PMID 11477107.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Song CZ, Keller K, Murata K; et al. (2002). "Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2". J. Biol. Chem. 277 (9): 7029–36. doi:10.1074/jbc.M108826200. PMID 11748222.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kaczynski JA, Conley AA, Fernandez Zapico M; et al. (2002). "Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter". Biochem. J. 366 (Pt 3): 873–82. doi:10.1042/BJ20020388. PMID 12036432.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Song A, Patel A, Thamatrakoln K; et al. (2002). "Functional domains and DNA-binding sequences of RFLAT-1/KLF13, a Krüppel-like transcription factor of activated T lymphocytes". J. Biol. Chem. 277 (33): 30055–65. doi:10.1074/jbc.M204278200. PMID 12050170.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nikolcheva T, Pyronnet S, Chou SY; et al. (2002). "A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes". J. Clin. Invest. 110 (1): 119–26. PMID 12093895.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mitsuma A, Asano H, Kinoshita T; et al. (2005). "Transcriptional regulation of FKLF-2 (KLF13) gene in erythroid cells". Biochim. Biophys. Acta. 1727 (2): 125–33. doi:10.1016/j.bbaexp.2004.12.007. PMID 15716005.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang P, Basu P, Redmond LC; et al. (2006). "A functional screen for Krüppel-like factors that regulate the human gamma-globin gene through the CACCC promoter element". Blood Cells Mol. Dis. 35 (2): 227–35. doi:10.1016/j.bcmd.2005.04.009. PMID 16023392.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ahn YT, Huang B, McPherson L; et al. (2007). "Dynamic interplay of transcriptional machinery and chromatin regulates "late" expression of the chemokine RANTES in T lymphocytes". Mol. Cell. Biol. 27 (1): 253–66. doi:10.1128/MCB.01071-06. PMID 17074812.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huang B, Ahn YT, McPherson L; et al. (2007). "Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription". J. Immunol. 178 (11): 7081–7. PMID 17513757.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

External links

• KLF13+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.