Hereditary elliptocytosis medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy== | ||
The vast majority of | * Management of hereditary elliptocytosis includes [[supportive therapy]]. | ||
* The vast majority of patients being diagnosed with hereditary elliptocytosis do not need any medication. | |||
[[Folate]] helps to reduce the extent of | * However HE patients with sever anemia may require [[blood transfusions]]. | ||
* [[Phototherapy]] may be required in new borns with [[jaundice]], specially in HPP and Neonatal poikilocytosis subtypes of HE. | |||
* There exists no definite treatment for membrane defect in HE. | |||
* Moreover these patients may have folate deficiency due to hemolysis, so folic acid supplementation or [[folic acid]] rich diet(green leafy vegetables) is advised. | |||
* [[Folate]] helps to reduce the extent of hemolysis in those with significant hemolysis due to hereditary elliptocytosis.<ref name="pmid21251470">{{cite journal| author=Barcellini W, Bianchi P, Fermo E, Imperiali FG, Marcello AP, Vercellati C et al.| title=Hereditary red cell membrane defects: diagnostic and clinical aspects. | journal=Blood Transfus | year= 2011 | volume= 9 | issue= 3 | pages= 274-7 | pmid=21251470 | doi=10.2450/2011.0086-10 | pmc=3136593 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21251470 }}</ref> | |||
==References== | ==References== | ||
Revision as of 19:04, 31 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
- Management of hereditary elliptocytosis includes supportive therapy.
- The vast majority of patients being diagnosed with hereditary elliptocytosis do not need any medication.
- However HE patients with sever anemia may require blood transfusions.
- Phototherapy may be required in new borns with jaundice, specially in HPP and Neonatal poikilocytosis subtypes of HE.
- There exists no definite treatment for membrane defect in HE.
- Moreover these patients may have folate deficiency due to hemolysis, so folic acid supplementation or folic acid rich diet(green leafy vegetables) is advised.
- Folate helps to reduce the extent of hemolysis in those with significant hemolysis due to hereditary elliptocytosis.[1]
References
- ↑ Barcellini W, Bianchi P, Fermo E, Imperiali FG, Marcello AP, Vercellati C; et al. (2011). "Hereditary red cell membrane defects: diagnostic and clinical aspects". Blood Transfus. 9 (3): 274–7. doi:10.2450/2011.0086-10. PMC 3136593. PMID 21251470.