Hemolytic anemia classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Hemolytic anemia can be divided into intravascular and extravascular based on whether the destruction of RBC occurs in the vessels or outside the vessels usually in spleen and liver. Extravascular hemolytic anemia are commoner than intravascular. There are many types of hemolytic anemias and the general classification of hemolytic anemia is either acquired or inherited.

Classification

Types of Hemolytic Anemias

Hemolytic anemias can be either genetic or acquired.

Genetic

Acquired

Acquired hemolytic anemia can be further divided into immune and non-immune mediated.

Immune mediated hemolytic anaemia (direct Coombs test is positive)

Non-immune mediated hemolytic anemia (direct Coombs test is negative)

References