Hemolytic anemia imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]

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Overview

Imaging modalities that can be used to assess organ involvement in hemolytic anemia include ultrasound, CT, and MRI.

Imaging Findings

  • Ultrasound: Ultrasound of the spleen is sometimes used to help assess for splenomegaly, or spleen enlargement. The benefit of ultrasound is that the size of the spleen can be measured with more precision compared to palpation by physical examination, and the size of the spleen can be monitored over time. Ultrasound can also be useful for assessing hepatomegaly, or liver enlargement, which can sometimes be seen in hemolytic anemia. Ultrasound is the most cost effective imaging test of the spleen.[1]
  • Magnetic resonance imaging, or MRI: MRI of the spleen can also be useful to assess for splenomegaly. However, this is a far more costly test compared to ultrasound or CT. If ultrasound or CT are unavailable or nondiagnostic, MRI can be considered. MRI can also accurately assess the size of the liver.[1]

References

  1. 1.0 1.1 1.2 Orphanidou-Vlachou E, Tziakouri-Shiakalli C, Georgiades CS (2014). "Extramedullary hemopoiesis". Semin Ultrasound CT MR. 35 (3): 255–62. doi:10.1053/j.sult.2013.12.001. PMID 24929265.

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