Hand-foot-and-mouth disease causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yamuna Kondapally, M.B.B.S[2]

Overview

Hand-foot-and-mouth disease may be caused by the following viral organisms Coxsackieviruses (Coxsackievirus A2, A4 to A10, A16, B2, B3, B5), Echoviruses (Echovirus 1, 4, 7, 19) and Enteroviruses (A71).

Causes

Hand-foot-and-mouth disease may be caused by the following organisms:[1]

Viruses

  • The viruses which are most common causes and responsible for larger outbreaks are Coxsackieviruses A16 and Enteroviruses A71.
  • Although enterovirus A71 is the cause of hand-foot-and mouth disease world wide, it is the major cause of largest outbreak in the Asia-Pacific regions.[2][3]
Viruses Serotypes
Coxsackieviruses A2, A4 to A10, A16, B2, B3, B5
Echoviruses 1, 4, 7, 19
Enteroviruses A71

United states

The most common cause of hand-foot-and-mouth disease in the United States is coxsackievirus A16, but can also be caused by other coxsackievirus.

References

  1. Hand-foot-and-mouth disease http://www.cdc.gov/hand-foot-mouth/about/transmission.html (2016) Accessed on October 18,2016
  2. Solomon T, Lewthwaite P, Perera D, Cardosa MJ, McMinn P, Ooi MH (2010). "Virology, epidemiology, pathogenesis, and control of enterovirus 71". Lancet Infect Dis. 10 (11): 778–90. doi:10.1016/S1473-3099(10)70194-8. PMID 20961813.
  3. Gao LD, Hu SX, Zhang H, Luo KW, Liu YZ, Xu QH; et al. (2014). "Correlation analysis of EV71 detection and case severity in hand, foot, and mouth disease in the Hunan Province of China". PLoS One. 9 (6): e100003. doi:10.1371/journal.pone.0100003. PMC 4062471. PMID 24941257.