Granulocytosis

WikiDoc Resources for Granulocytosis
Articles
Most recent articles on Granulocytosis Most cited articles on Granulocytosis Review articles on Granulocytosis Articles on Granulocytosis in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Granulocytosis Images of Granulocytosis Photos of Granulocytosis Podcasts & MP3s on Granulocytosis Videos on Granulocytosis
Evidence Based Medicine
Cochrane Collaboration on Granulocytosis Bandolier on Granulocytosis TRIP on Granulocytosis
Clinical Trials
Ongoing Trials on Granulocytosis at Clinical Trials.gov Trial results on Granulocytosis Clinical Trials on Granulocytosis at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Granulocytosis NICE Guidance on Granulocytosis NHS PRODIGY Guidance FDA on Granulocytosis CDC on Granulocytosis
Books
Books on Granulocytosis
News
Granulocytosis in the news Be alerted to news on Granulocytosis News trends on Granulocytosis
Commentary
Blogs on Granulocytosis
Definitions
Definitions of Granulocytosis
Patient Resources / Community
Patient resources on Granulocytosis Discussion groups on Granulocytosis Patient Handouts on Granulocytosis Directions to Hospitals Treating Granulocytosis Risk calculators and risk factors for Granulocytosis
Healthcare Provider Resources
Symptoms of Granulocytosis Causes & Risk Factors for Granulocytosis Diagnostic studies for Granulocytosis Treatment of Granulocytosis
Continuing Medical Education (CME)
CME Programs on Granulocytosis
International
Granulocytosis en Espanol Granulocytosis en Francais
Business
Granulocytosis in the Marketplace Patents on Granulocytosis
Experimental / Informatics
List of terms related to Granulocytosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

• Granulocytosis is defined as the presence of an increased number of granulocytes, a category of white blood cells present in the peripheral blood. Often, the word refers to an increased neutrophil granulocyte count, as neutrophils are the main granulocytes.

• An increase in eosinophil granulocyte is known as eosinophilia.

• Granulocytosis can be a feature of a number of diseases:

• Infection, especially bacterial
• Malignancy, most notably leukemia (it is the main feature of chronic myelogenous leukemia, CML)
• Autoimmune disease

• In cardiovascular disease, increased white blood cell counts have been shown to indicate a worse prognosis.

Differential Diagnosis of Causes of Granulocytosis

By Organ System

Cardiovascular	No underlying causes
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Aminophylline, Dinoprostone, Filgrastim, Granulocyte colony stimulating factor, Granulocyte-macrophage colony stimulating factor, Lithium, Sulprostone
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Acute pancreatitis, Gallbladder empyema
Genetic	Acute intermittent porphyria, Hereditary neutrophilia, Hyperimmunoglobulinemia D and periodic fever syndrome, Leukocyte adhesion deficiency type 1, Leukocyte adhesion deficiency type 2, Leukocyte adhesion deficiency type 3, Recurrent hereditary polyserositis
Hematologic	Acute intermittent porphyria, Leukemoid reaction, Leukocyte adhesion deficiency type 1, Leukocyte adhesion deficiency type 2, Leukocyte adhesion deficiency type 3, Lymphangitis, Polycythaemia rubra vera, Recurrent hereditary polyserositis
Iatrogenic	Splenectomy
Infectious Disease	Congenital syphilis, Hantavirus
Musculoskeletal / Ortho	No underlying causes
Neurologic	No underlying causes
Nutritional / Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	Acute myeloid leukemia, Acute promyelocytic leukemia, Chronic myeloid leukaemia, Mast cell leukemia, Polycythaemia rubra vera
Opthalmologic	No underlying causes
Overdose / Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	Bronchiolitis obliterans organizing pneumonia, Extrinsic allergic alveolitis, Wegener granulomatosis, Severe acute respiratory syndrome
Renal / Electrolyte	Wegener granulomatosis
Rheum / Immune / Allergy	Adult-onset Still disease, Urate crystal arthropathy, Wegener granulomatosis
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

In alphabetical order

• Acute intermittent porphyria
• Acute myeloid leukemia
• Acute pancreatitis
• Acute promyelocytic leukemia
• Adult-onset Still's disease
• Aminophylline
• Bronchiolitis obliterans organizing pneumonia
• Chronic myeloid leukaemia
• Congenital syphilis
• Dinoprostone
• Extrinsic allergic alveolitis
• Filgrastim
• Gallbladder empyema
• Granulocyte colony stimulating factor
• Granulocyte-macrophage colony stimulating factor
• Hantavirus
• Hereditary neutrophilia
• Hyperimmunoglobulinemia D and periodic fever syndrome
• Leukocyte adhesion deficiency type 1
• Leukocyte adhesion deficiency type 2
• Leukocyte adhesion deficiency type 3
• Leukemoid reaction
• Lithium
• Lymphangitis
• Mast cell leukemia
• Polycythaemia rubra vera
• Recurrent hereditary polyserositis
• Severe acute respiratory syndrome
• Splenectomy
• Sulprostone
• Urate crystal arthropathy
• Wegener granulomatosis

Related Chapters

• Agranulocytosis
• Complete blood count