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| ==Risk Factors== | | ==Risk Factors== |
| * [[Hypertension]]
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| * [[Diabetes]]
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| * [[Hypercholesterolemia]]
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| * [[Hyperparathyroidism]]
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| * [[Overweight]]
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| * [[Alcohol abuse]]- Alcohol intake often causes acute attacks of gout and hereditary factors may contribute to the elevation of uric acid.
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| * Foods that are rich in [[purines]], such as salmon, sardines, organ meats, asparagus, mushrooms and herring.
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| * Medications such as [[Bicalutamide]], [[hydrochlorothiazide]], [[niacin]], [[aspirin]], [[cyclosporine]], [[Ritonavir]], [[pyrazinamide]] and [[ethambutol]], and some drugs used to treat cancer.
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| * Family history of gout
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| * Male, or female after [[menopause]]
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| A seasonal link also may exist, with significantly higher incidence of acute gout attacks occurring in the spring.<ref>{{cite web | author =Schlesinger N, Gowin KM, Baker DG, Beutler AM, Hoffman BI, Schumacher HR Jr. | title = Acute gouty arthritis is seasonal. | url=http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=9489831&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus | accessdate = 2007-09-27}}</ref> <ref>{{cite web | author = Gallerani M, Govoni M, Mucinelli M, Bigoni M, Trotta F, Manfredini R. | title = Seasonal variation in the onset of acute microcrystalline arthritis. | url=http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=10534553&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus| accessdate = 2007-09-27}}</ref>
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| Gout also can develop as co-morbidity of other diseases, including polycythaemia, [[leukaemia]], intake of [[cytotoxic]]s, [[obesity]], [[diabetes]], [[hypertension]], [[renal]] disorders, and [[hemolytic anemia]]. This form of gout is often called secondary gout. [[Diuretic]]s (particularly [[thiazide]] diuretics) have traditionally been blamed for precipitating attacks of gout, but a Dutch case-control study from 2006 appears to cast doubt on this conclusion.<ref>{{cite journal | author = Janssens H, van de Lisdonk E, Janssen M, van den Hoogen H, Verbeek A | title = Gout, not induced by diuretics? A case-control study from primary care | journal = Ann Rheum Dis | volume = 65 | issue = 8 | pages = 1080–3 | year = 2006 | id = PMID 16291814 | doi=10.1136/ard.2005.040360}}</ref>
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |