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==History and Symptoms== | ==History and Symptoms== | ||
===History=== | |||
Obtaining history is an important aspect in making a [[diagnosis]] of Goodpasture syndrome. It provides insight into cause, precipitating factors and associated [[Comorbidity|comorbid]] conditions. Complete history will help determine the correct therapy and helps in determining the [[prognosis]]. Specific histories about the [[symptoms]] (duration, onset, progression), associated [[symptoms]], drug usage have to be obtained. Specific areas of focus when obtaining the history, are outlined below: | |||
*Past medical history (recent upper respiratory tract [[infection]]) | |||
*Breathing difficulty | |||
*Urinary changes ([[frequency]], dysuria or color change) | |||
*[[Fatigue]] | |||
*[[Fever]] | |||
Symptoms may occur very slowly over months or even years, but they often develop quickly over days to weeks. | Symptoms may occur very slowly over months or even years, but they often develop quickly over days to weeks. | ||
Revision as of 01:25, 22 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]
Overview
Obtaining a complete history is an important aspect of making a diagnosis of Goodpasture syndrome, as it can provide insight into cause, precipitating factors, and associated underlying conditions. Symptoms may develop acutely or rapidly affecting the renal and pulmonary system. Symptoms of Goodpasture syndrome include, malaise, pyrexia and chills and arthralgia, fatigue, lethargy, pallor, and anorexia.[1]
History and Symptoms
History
Obtaining history is an important aspect in making a diagnosis of Goodpasture syndrome. It provides insight into cause, precipitating factors and associated comorbid conditions. Complete history will help determine the correct therapy and helps in determining the prognosis. Specific histories about the symptoms (duration, onset, progression), associated symptoms, drug usage have to be obtained. Specific areas of focus when obtaining the history, are outlined below:
- Past medical history (recent upper respiratory tract infection)
- Breathing difficulty
- Urinary changes (frequency, dysuria or color change)
- Fatigue
- Fever
Symptoms may occur very slowly over months or even years, but they often develop quickly over days to weeks.
Loss of appetite, fatigue, weakness are often seen at first.[1] [2]
Pulmonary symptoms may include:[1]
- Hemoptysis
- Dry cough
- Dyspnea
- Anemia
- Pulmonary hemorrhage that may lead to respiratory failure
- less frequently may cause angina pectoris
Renal and other symptoms include:[1]
- Dysuria
- Hematuria
- Edema of the hands and feet
- Uremia
- Hypertension
- Back pain below the ribs
- Hearing loss
- Vertigo
References
- ↑ 1.0 1.1 1.2 1.3 Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.
- ↑ Hellmark T, Segelmark M (2014). "Diagnosis and classification of Goodpasture's disease (anti-GBM)". J Autoimmun. 48-49: 108–12. doi:10.1016/j.jaut.2014.01.024. PMID 24456936.