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==Causes==
==Causes==


Goodpasture syndrome may be caused by either viral or bacterial infections, occupational, environmental or behavioral risk factors.  
Goodpasture syndrome may be caused by either viral or bacterial infections, occupational, environmental or behavioral risk factors.<ref name="pmid25838905">{{cite journal |vauthors=Cranfield A, Mathavakkannan S |title=Goodpasture's disease following extracorporeal shock wave lithotripsy: a case report & literature review |journal=Clin Case Rep |volume=3 |issue=3 |pages=160–4 |date=March 2015 |pmid=25838905 |pmc=4377247 |doi=10.1002/ccr3.190 |url=}}</ref>


'''Viral and bacterial risk factors causing Goodpasture syndrome'''  
'''Viral and bacterial risk factors causing Goodpasture syndrome'''  
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* Mineral dust
* Mineral dust
* D-penicillamine
* D-penicillamine


==References==
==References==

Revision as of 00:57, 22 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3]

Overview

There are no known direct causes for Goodpasture syndrome. Common risk factors for Goodpasture syndrome are viral or bacterial infections and certain environmental and behavioral risk factors such as smoking, hydrocarbons, formaldehyde and cocaine use.[1]

Causes

Goodpasture syndrome may be caused by either viral or bacterial infections, occupational, environmental or behavioral risk factors.[2]

Viral and bacterial risk factors causing Goodpasture syndrome

It is not clear how bacterial or viral infections play a role in Goodpasture syndrome. However, it is presumed that infections such as the influenza virus may play a role in the disease because of cross-reactivity in the basement membrane.[3]

Occupational, Environmental and Behavioral risk factors causing Goodpasture syndrome[1] [4] [5]

Occupational, environmental and behavioral risk factors that cause Goodpasture syndrome include:

  • Smoking tobacco
  • Exposure to organic solvents
  • Exposure to hydrocarbons
  • Cocaine
  • Silicosis
  • Mineral dust
  • D-penicillamine

References

  1. 1.0 1.1 Hellmark T, Segelmark M (2014). "Diagnosis and classification of Goodpasture's disease (anti-GBM)". J Autoimmun. 48-49: 108–12. doi:10.1016/j.jaut.2014.01.024. PMID 24456936.
  2. Cranfield A, Mathavakkannan S (March 2015). "Goodpasture's disease following extracorporeal shock wave lithotripsy: a case report & literature review". Clin Case Rep. 3 (3): 160–4. doi:10.1002/ccr3.190. PMC 4377247. PMID 25838905.
  3. Wilson CB, Dixon FJ (1973). "Anti-glomerular basement membrane antibody-induced glomerulonephritis". Kidney Int. 3 (2): 74–89. PMID 4571918.
  4. Bal A, Das A, Gupta D, Garg M (2014). "Goodpasture's Syndrome and p-ANCA Associated Vasculitis in a Patient of Silicosiderosis: An Unusual Association". Case Rep Pulmonol. 2014: 398238. doi:10.1155/2014/398238. PMC 4202243. PMID 25349763.
  5. Bombassei GJ, Kaplan AA (1992). "The association between hydrocarbon exposure and anti-glomerular basement membrane antibody-mediated disease (Goodpasture's syndrome)". Am J Ind Med. 21 (2): 141–53. PMID 1536151.

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