Gallstone disease laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings are usually normal among patients with uncomplicated gallstone disease, both during asymptomatic periods and during attacks of | There are no diagnostic laboratory findings associated with an uncomplicated case of gallstone disease. Laboratory findings are usually normal among patients with uncomplicated gallstone disease, both during asymptomatic periods and during attacks of [[biliary colic]]. Abnormal [[blood tests]] including ([[leukocytosis]], [[Liver function tests|elevated liver]] or [[Pancreatic lipase|pancreas tests]]) suggest the development of a complication of gallstone disease, such as [[acute cholecystitis]], [[acute cholangitis]], or [[acute pancreatitis]]. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory studies suggesting development of complications include: | |||
* | *'''Liver biochemical tests:''' | ||
** | **Serum [[aminotransferases]] | ||
** | **Total [[bilirubin]] | ||
**[[Alkaline phosphatase]] | **[[Alkaline phosphatase]] | ||
**[[ | ***All maybe abnormal in patients with [[hepatitis]], [[biliary tract]] obstruction, or (less commonly) [[acute cholecystitis]] | ||
**[[ | *'''Serum [[amylase]]''' | ||
*'''Serum [[lipase]]''' | |||
**Serum [[amylase]] and serum [[lipase]] are elevated in [[acute pancreatitis]] | |||
*'''[[Complete blood count|Complete blood count]] (CBC)''' | |||
**CBC may show an elevated [[White blood cell|white blood cell count]] in patients with acute [[cholecystitis]] or acute [[cholangitis]] | |||
*'''Urine analysis''' | |||
**Urine analysis may indicate a [[urinary tract infection]] or [[ureteral]] [[calculi]]<ref name="pmid23533021">{{cite journal |vauthors=Poupon R, Rosmorduc O, Boëlle PY, Chrétien Y, Corpechot C, Chazouillères O, Housset C, Barbu V |title=Genotype-phenotype relationships in the low-phospholipid-associated cholelithiasis syndrome: a study of 156 consecutive patients |journal=Hepatology |volume=58 |issue=3 |pages=1105–10 |year=2013 |pmid=23533021 |doi=10.1002/hep.26424 |url=}}</ref><ref name="pmid8363172">{{cite journal |vauthors=Ransohoff DF, Gracie WA |title=Treatment of gallstones |journal=Ann. Intern. Med. |volume=119 |issue=7 Pt 1 |pages=606–19 |year=1993 |pmid=8363172 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | |||
[[Category:Gastroenterology]] | |||
[[Category:Hepatology]] | |||
[[Category:Surgery]] | |||
[[Category:Disease]] | |||
Latest revision as of 21:48, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
There are no diagnostic laboratory findings associated with an uncomplicated case of gallstone disease. Laboratory findings are usually normal among patients with uncomplicated gallstone disease, both during asymptomatic periods and during attacks of biliary colic. Abnormal blood tests including (leukocytosis, elevated liver or pancreas tests) suggest the development of a complication of gallstone disease, such as acute cholecystitis, acute cholangitis, or acute pancreatitis.
Laboratory Findings
Laboratory studies suggesting development of complications include:
- Liver biochemical tests:
- Serum aminotransferases
- Total bilirubin
- Alkaline phosphatase
- All maybe abnormal in patients with hepatitis, biliary tract obstruction, or (less commonly) acute cholecystitis
- Serum amylase
- Serum lipase
- Serum amylase and serum lipase are elevated in acute pancreatitis
- Complete blood count (CBC)
- CBC may show an elevated white blood cell count in patients with acute cholecystitis or acute cholangitis
- Urine analysis
- Urine analysis may indicate a urinary tract infection or ureteral calculi[1][2]
References
- ↑ Poupon R, Rosmorduc O, Boëlle PY, Chrétien Y, Corpechot C, Chazouillères O, Housset C, Barbu V (2013). "Genotype-phenotype relationships in the low-phospholipid-associated cholelithiasis syndrome: a study of 156 consecutive patients". Hepatology. 58 (3): 1105–10. doi:10.1002/hep.26424. PMID 23533021.
- ↑ Ransohoff DF, Gracie WA (1993). "Treatment of gallstones". Ann. Intern. Med. 119 (7 Pt 1): 606–19. PMID 8363172.