Gallstone disease future or investigational therapies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
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Overview
Electrohydraulic lithotripsy is the latest advancement in the removal of gallstones in a nonsurgical manner boasting success rates of over 90%.[1][2]
Future or Investigational Therapies
Electrohydraulic lithotripsy (EHL) works on the same principle as ERCP. A digital single-operator cholangioscope known as "SpyGlass" is passed through a duodenoscope passed through the oral passage, however, unlike ERCP, no xrays are needed to visualise the stones. Once the stones are reached, a powerful burst of electrical currents are released to shatter stones. The main risk with EHL is that the common bile duct may be perforated and bleeding, as well as injury to the surrounding epithelium may occur.[3][4][5][6]
References
- ↑ Siegel JH, Ben-Zvi JS, Pullano WE (1990). "Endoscopic electrohydraulic lithotripsy". Gastrointest. Endosc. 36 (2): 134–6. PMID 2335279.
- ↑ Binmoeller KF, Brückner M, Thonke F, Soehendra N (1993). "Treatment of difficult bile duct stones using mechanical, electrohydraulic and extracorporeal shock wave lithotripsy". Endoscopy. 25 (3): 201–6. doi:10.1055/s-2007-1010293. PMID 8519238.
- ↑ Lee JG, Leung JW (1996). "Endoscopic management of difficult common bile duct stones". Gastrointest. Endosc. Clin. N. Am. 6 (1): 43–55. PMID 8903562.
- ↑ Craigie JE, Adams DB, Byme TK, Tagge EP, Tarnasky PR, Cunningham JT, Hawes RH (1998). "Endoscopic electrohydraulic lithotripsy in the management of pancreatobiliary lithiasis". Surg Endosc. 12 (5): 405–8. PMID 9569358.
- ↑ Adamek HE, Maier M, Jakobs R, Wessbecher FR, Neuhauser T, Riemann JF (1996). "Management of retained bile duct stones: a prospective open trial comparing extracorporeal and intracorporeal lithotripsy". Gastrointest. Endosc. 44 (1): 40–7. PMID 8836715.
- ↑ Adamek HE, Schneider AR, Adamek MU, Jakobs R, Buttmann A, Benz C, Riemann JF (1999). "Treatment of difficult intrahepatic stones by using extracorporeal and intracorporeal lithotripsy techniques: 10 years' experience in 55 patients". Scand. J. Gastroenterol. 34 (11): 1157–61. PMID 10582769.