Fibroma differential diagnosis: Difference between revisions

Jump to navigation Jump to search
No edit summary
 
(24 intermediate revisions by 4 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Fibroma}}
[[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Fibroma]]
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}}{{M.N}}, {{Simrat}}
==Overview==
==Overview==
Oral fibroma must be differentiated from [[squamous papilloma]], [[giant cell fibroma]], [[neurofibroma]], [[peripheral giant cell]] granuloma, [[mucocele]], and benign and [[malignant salivary gland tumors]]. [[Non-ossifying fibroma]] must be differentiated from [[fibrous cortical defect]], [[aneurysmal bone cyst]], [[chondromyxoid fibroma]], [[fibrous dysplasia]], [[desmoplastic fibroma]], [[giant cell tumor]] of bone, and spindle cell lesions of bone. [[Ossifying fibroma]] must be differentiated from ossifying fibroma, [[fibrous dysplasia]], [[adamantinoma]], and [[osteoid osteoma]]. [[Chondromyxoid fibroma]] must be differentiated from [[aneurysmal bone cyst]] (ABC), [[giant cell tumor]] of bone (GCT), [[non-ossifying fibroma]], [[chondroblastoma]], [[chondrosarcoma]], and phosphaturic mesenchymal tumor. [[Desmoplastic fibroma]] must be differentiated from [[giant cell tumor]] of bone (GCT), [[non- ossifying fibroma]] (NOF), fibrous dysplasia, low grade fibrosarcoma, unicameral bone cyst, chondromyxoid fibroma, periosteal desmoids, eosinophilic granuloma, low-grade intraosseous osteosarcoma, [[adamantinoma]], and distant metastasis.
==Differential Diagnosis==
==Differential Diagnosis==
{| style="border: 0px; font-size: 90%; margin: 3px; width: 600px" align=center
{| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
|valign=top|
|valign=top|
|+
|+
Line 14: Line 16:
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*Large pedunculated subserosal uterine leiomyoma
*Large pedunculated subserosal uterine leiomyoma
*[[Thecoma]]
*[[Leiomyoma]]
*[[Fibrosarcoma]]
*Metastatic metaplastic carcinoma
*Endometriosis with extensive fibrosis.
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Non-ossifying fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Fibrous cortical defect]]
*[[Aneurysmal bone cyst]]
*[[Chondromyxoid fibroma]]
*Fibrous dysplasia
*[[Desmoplastic fibroma]]
*[[Giant cell tumor]] of bone
*Spindle cell lesions of bone
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Ossifying Fibroma
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Fibrous dysplasia]]
*[[Adamantinoma]]
*[[Osteoid osteoma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Chondromyxoid Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Aneurysmal bone cyst]] (ABC)
*[[Giant cell tumor]] of bone (GCT)
*[[Non ossifying fibroma]]
*[[Chondroblastoma]]
*[[Chondrosarcoma]]
*Phosphaturic mesenchymal tumor
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Desmoplastic Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Giant cell tumor]] of bone (GCT)
*[[Non ossifying fibroma]] (NOF)
*[[Fibrous dysplasia]]
*Low grade [[fibrosarcoma]]
*Unicameral bone cyst
*[[Chondromyxoid fibroma]]
*Periosteal desmoids
*Eosinophilic granuloma
*Low-grade intraosseous osteosarcoma
*[[Adamantinoma]]
*Distant metastasis
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Pleural Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
Considerations for extremely well defined lesions include:
*[[Pleural lipoma]]
*Pleural [[fibrosarcoma]]
*[[Intercostal nerve neurilemoma]] (schwannoma)
If not extremely well defined, broader considerations include:
*Organised inflammation
*Peripheral bronchogenic carcinoma
*Solitary pleural metastasis
Also consider the differential for a single pleural mass which includes the following:
*Pleural tumors
**Solitary fibrous tumour of the pleura (pleural fibroma)
**Mesothelioma
**Localised mediastinal malignant mesothelioma
*Metastatic pleural disease, particularly from [[adenocarcinomas]]
*Pleural lymphoma
*Invasive thymoma
*Lipoma
*[[Pleural effusion]]
*[[Empyema]]
*[[Haemothorax]]
*[[Ewing sarcoma]] of chest wall, Askin tumor
*Intercostal nerve neurilemmoma
*Splenosis
*[[Tuberculosis]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Renal Medullary Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*Renal myxoma
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Cemento-ossifying Fibroma
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Fibrous dysplasia]]
*Ameloblastic fibro odontoma
*[[Odontoma]]
*Calcifying epithelial odontogenic tumour (Pindborg tumour)
*Odontogenic cyst
*Calcifying odontogenic cyst (Gorlin cyst)
*[[Osteochondroma]]
*[[Osteosarcoma]]
*[[Chondrosarcoma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Desmoplastic fibroblastoma]] (Collagenous fibroma)
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Fibromatosis]]
*[[Elastofibroma]]
*Low-grade fibromyxoid sarcoma.
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:
:[[Ameloblastic Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*57%
*Ameloblastoma
|-
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:30-44 years
:[[Giant cell fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |
*9%
*[[Squamous Papilloma]]
*Irritation fibroma
*Pyogenic granuloma
*Peripheral giant cell granuloma.
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:Oral Fibroma
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Squamous Papilloma]]
*[[Giant cell fibroma]]
*[[Neurofibroma]]
*Peripheral giant cell granuloma
*[[Mucocele]]
*Benign and [[malignant salivary gland]] tumors
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Uterine Fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Uterine leiomyosarcoma]]
*Uterine smooth muscle tumors of uncertain malignant potential
*Uterine lipoleiomyoma
*Ovarian masses
*Focal myometrial contraction (Braxton Hicks contraction): especially if seen during pregnancy
*Focal [[adenomyosis]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Peripheral odontogenic fibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*Inflammatory gingival hyperplasia
*Peripheral [[cemento-ossifying fibroma]]
*Peripheral [[giant cell granuloma]]
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
:[[Elastofibroma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*Spindle cell lipoma
*Nuchal-type fibroma
*Fibromatosis colli
|-
|-
|}
|}
Line 33: Line 173:
{{WS}}
{{WS}}


{{Soft tissue tumors and sarcomas}}
[[Category:Gynecology]]
 
[[Category:Dermatology]]
[[Category:Gynecology]]  
[[Category:Oncology]]  
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Needs content]]
[[Category:Up-To-Date]]
[[Category:Medicine]]

Latest revision as of 16:36, 5 July 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2], Simrat Sarai, M.D. [3]

Overview

Oral fibroma must be differentiated from squamous papilloma, giant cell fibroma, neurofibroma, peripheral giant cell granuloma, mucocele, and benign and malignant salivary gland tumors. Non-ossifying fibroma must be differentiated from fibrous cortical defect, aneurysmal bone cyst, chondromyxoid fibroma, fibrous dysplasia, desmoplastic fibroma, giant cell tumor of bone, and spindle cell lesions of bone. Ossifying fibroma must be differentiated from ossifying fibroma, fibrous dysplasia, adamantinoma, and osteoid osteoma. Chondromyxoid fibroma must be differentiated from aneurysmal bone cyst (ABC), giant cell tumor of bone (GCT), non-ossifying fibroma, chondroblastoma, chondrosarcoma, and phosphaturic mesenchymal tumor. Desmoplastic fibroma must be differentiated from giant cell tumor of bone (GCT), non- ossifying fibroma (NOF), fibrous dysplasia, low grade fibrosarcoma, unicameral bone cyst, chondromyxoid fibroma, periosteal desmoids, eosinophilic granuloma, low-grade intraosseous osteosarcoma, adamantinoma, and distant metastasis.

Differential Diagnosis

Type of Fibroma Differential Diagnosis
Ovarian fibroma
  • Large pedunculated subserosal uterine leiomyoma
  • Thecoma
  • Leiomyoma
  • Fibrosarcoma
  • Metastatic metaplastic carcinoma
  • Endometriosis with extensive fibrosis.
Non-ossifying fibroma
Ossifying Fibroma
Chondromyxoid Fibroma
Desmoplastic Fibroma
Pleural Fibroma

Considerations for extremely well defined lesions include:

If not extremely well defined, broader considerations include:

  • Organised inflammation
  • Peripheral bronchogenic carcinoma
  • Solitary pleural metastasis

Also consider the differential for a single pleural mass which includes the following:

Renal Medullary Fibroma
  • Renal myxoma
Cemento-ossifying Fibroma
Desmoplastic fibroblastoma (Collagenous fibroma)
Ameloblastic Fibroma
  • Ameloblastoma
Giant cell fibroma
Oral Fibroma
Uterine Fibroma
  • Uterine leiomyosarcoma
  • Uterine smooth muscle tumors of uncertain malignant potential
  • Uterine lipoleiomyoma
  • Ovarian masses
  • Focal myometrial contraction (Braxton Hicks contraction): especially if seen during pregnancy
  • Focal adenomyosis
Peripheral odontogenic fibroma
Elastofibroma
  • Spindle cell lipoma
  • Nuchal-type fibroma
  • Fibromatosis colli

References

Template:WH Template:WS