Familial adenomatous polyposis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings that may present with familial adenomatous polyposis include [[anemia]] due to [[ | Laboratory findings that may present with familial adenomatous polyposis include [[anemia]] due to [[gastrointestinal bleeding]] and abnormal [[liver function tests]] due to [[Colorectal cancer|colon cancer]] metastasis. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Common laboratory findings that may present with familial adenomatous polyposis are:<ref name="pmid11446392">{{cite journal |vauthors=Beech D, Pontius A, Muni N, Long WP |title=Familial adenomatous polyposis: a case report and review of the literature |journal=J Natl Med Assoc |volume=93 |issue=6 |pages=208–13 |year=2001 |pmid=11446392 |pmc=2594024 |doi= |url=}}</ref><ref name="pmid20301519">{{cite journal |vauthors=Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ |title=APC-Associated Polyposis Conditions. |journal= |volume= |issue= |pages= |year= |pmid=20301519 |doi= |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | Common laboratory findings that may present with familial adenomatous polyposis are:<ref name="pmid11446392">{{cite journal |vauthors=Beech D, Pontius A, Muni N, Long WP |title=Familial adenomatous polyposis: a case report and review of the literature |journal=J Natl Med Assoc |volume=93 |issue=6 |pages=208–13 |year=2001 |pmid=11446392 |pmc=2594024 |doi= |url=}}</ref><ref name="pmid20301519">{{cite journal |vauthors=Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ |title=APC-Associated Polyposis Conditions. |journal= |volume= |issue= |pages= |year= |pmid=20301519 |doi= |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | ||
*[[Complete blood count]] | *'''[[Complete blood count]]:''' | ||
**[[ | **Low [[hemoglobin]] due to [[gastrointestinal bleeding]] (normal - 12.1 to 15.1 g/dl for women and 13.8 to 17.2 g/dl for men) | ||
**Elevated [[Platelet|platelet count]] (normal | **Elevated [[Platelet|platelet count]] (normal - 150,000 to 450,000 mcL) | ||
*[[Liver function tests|Liver function test]] due to colon cancer [[metastasis]] | *[[Liver function tests|'''Liver function test''']] : | ||
**High aspartate aminotransferase (AST) (normal | **The liver function tests may be deranged due to colon cancer [[metastasis]]. The findings may include: | ||
**High alanine aminotransferase (ALT) (normal | ***High [[Aspartate transaminase|aspartate aminotransferase]] ([[Aspartate transaminase|AST]]) (normal - 8 to 48 U/L) | ||
***High [[Alanine transaminase|alanine aminotransferase]] ([[Alanine transaminase|ALT]]) (normal - 7 to 55 units per liter U/L) | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
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[[Category:Medicine]] | [[Category:Medicine]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Oncology]] | |||
[[Category:Up-To-Date]] | |||
Latest revision as of 21:43, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
Laboratory findings that may present with familial adenomatous polyposis include anemia due to gastrointestinal bleeding and abnormal liver function tests due to colon cancer metastasis.
Laboratory Findings
Common laboratory findings that may present with familial adenomatous polyposis are:[1][2][3]
- Complete blood count:
- Low hemoglobin due to gastrointestinal bleeding (normal - 12.1 to 15.1 g/dl for women and 13.8 to 17.2 g/dl for men)
- Elevated platelet count (normal - 150,000 to 450,000 mcL)
- Liver function test :
- The liver function tests may be deranged due to colon cancer metastasis. The findings may include:
- High aspartate aminotransferase (AST) (normal - 8 to 48 U/L)
- High alanine aminotransferase (ALT) (normal - 7 to 55 units per liter U/L)
- The liver function tests may be deranged due to colon cancer metastasis. The findings may include:
References
- ↑ Beech D, Pontius A, Muni N, Long WP (2001). "Familial adenomatous polyposis: a case report and review of the literature". J Natl Med Assoc. 93 (6): 208–13. PMC 2594024. PMID 11446392.
- ↑ Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean L, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ. "APC-Associated Polyposis Conditions". PMID 20301519. Vancouver style error: initials (help)
- ↑ Half, Elizabeth; Bercovich, Dani; Rozen, Paul (2009). "Familial adenomatous polyposis". Orphanet Journal of Rare Diseases. 4 (1): 22. doi:10.1186/1750-1172-4-22. ISSN 1750-1172.