Coxsackie virus
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Usama Talib, BSc, MD [2]
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Coxsackie Virus |
Overview
Coxsackie (virus) is a cytolytic virus of the Picornaviridae family, an enterovirus (a group containing the polioviruses, coxsackieviruses, and echoviruses). There are 61 non-polio enteroviruses that can cause disease in humans, of which 23 are Coxsackie A viruses (6 are Coxsackie B viruses). Enterovirus are the second most common viral infectious agents in humans (after the rhinoviruses)
Classification
Coxsackie viruses consist of Coxsackie A virus and Coxsackie B virus. Coxsackie B virus has a subdicvision called Coxsackie B4 virus.
| Coxsackie Virus | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Coxsackie A virus | Coxsackie B virus[1] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Common Coxsackie B virus diseases | Coxsackie B4 virus diseases | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| • Hand, foot and mouth disease • Acute hemorrhagic conjunctivitis • Herpangina • Aseptic meningitis | • Pericarditis • Myocarditis • Pericardial effusion • Pleurodynia • Hepatitis | • Diabetes mellitus • Acute flaccid myelitis[2] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Differential Diagnosis
Coxsackie A virus and Coxsackie B virus can cause multiple diseases in humans. The wide array of diseases caused by Coxsackie viruses can be differentiated from one another easily on the basis of involvement of the organs systems, clinical presentation and diagnostic techniques.
| Virus Type | Disease | Clinical Features | Diagnosis |
|---|---|---|---|
| Coxscakie A virus | Hand foot and mouth disease | ||
| Acute hemorrhagic conjunctivitis | |||
| Herpangina | |||
| Aseptic Meningitis | |||
| Coxsackie B virus | Pericarditis | ||
| Myocarditis | |||
| Pericardial effusion | |||
| Pleurodynia | |||
| Hepatitis |
Template:Baltimore classification Template:Viral diseases
- ↑ Fields, Bernard N. (1985). Fields Virology. New York: Raven Press. pp. 739–794. ISBN 0-88167-026-X. Unknown parameter
|coauthors=ignored (help) - ↑ Cho SM, MacDonald S, Frontera JA (2017). "Coxsackie B3/B4-Related Acute Flaccid Myelitis". Neurocrit Care. doi:10.1007/s12028-017-0377-8. PMID 28324262.