Chronic stable angina laboratory findings

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Chronic stable angina Microchapters

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Historical Perspective

Classification

Classic
Chronic Stable Angina
Atypical
Walk through Angina
Mixed Angina
Nocturnal Angina
Postprandial Angina
Cardiac Syndrome X
Vasospastic Angina

Differentiating Chronic Stable Angina from Acute Coronary Syndromes

Pathophysiology

Epidemiology and Demographics

Risk Stratification

Pretest Probability of CAD in a Patient with Angina

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Laboratory Findings

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Myocardial Perfusion Scintigraphy with Thallium

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Coronary Angiography

Treatment

Medical Therapy

Revascularization

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Hybrid Coronary Revascularization

Alternative Therapies for Refractory Angina

Transmyocardial Revascularization (TMR)
Spinal Cord Stimulation (SCS)
Enhanced External Counter Pulsation (EECP)
ACC/AHA Guidelines for Alternative Therapies in patients with Refractory Angina

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Noninvasive Testing in Asymptomatic Patients
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Editors-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Cafer Zorkun, M.D., Ph.D. [2]; Associate Editor-in-Chief: Smita Kohli, M.D.

Laboratory Tests

  • Routine hematologic tests are necessary to exclude significant anemia
  • Homocysteinemia has been found to be a risk factor for CAD. Folate, vitamin B12 and vitamin B6 can lower the homocysteine level. Although the therapeutic implications of lowering homocysteine levels have not been fully defined, homocysteine concentrations should be measured in patients with a strong family history of coronary disease, especially if it is not explained by traditional risk factors.

ACC / AHA Guidelines- Recommendations for Initial Laboratory Tests for Diagnosis (DO NOT EDIT)[1]

Class I

1. Hemoglobin. (Level of Evidence: C)

2. Fasting glucose. (Level of Evidence: C)

3. Fasting lipid panel, including total cholesterol, HDL cholesterol, triglycerides, and calculated LDL cholesterol. (Level of Evidence: C)

ESC Guidelines for laboratory investigation in initial assessment of stable angina (DO NOT EDIT)[2]

Class I (in all patients)

1. Fasting lipid profile, including total cholesterol, LDL, HDL, and triglycerides. (Level of Evidence: B)

2. Fasting glucose. (Level of Evidence: B)

3. Full blood count including Hemoglobin and white cell count. (Level of Evidence: B)

4. Creatinine. (Level of Evidence: C)

Class I (if specifically indicated on the basis of clinical evaluation)

1. Markers of myocardial damage if evaluation suggests clinical instability or ACS. (Level of Evidence: A)

2. Thyroid function if clinically indicated. (Level of Evidence: C)

Class IIa

1. Oral glucose tolerance test. (Level of Evidence: B)

Class IIb

1. Hs-C-reactive protein. (Level of Evidence: B)

2. Lipoprotein a, ApoA, and ApoB . (Level of Evidence: B)

3. Homocysteine. (Level of Evidence: B)

4. HbA1c. (Level of Evidence: B)

5. NT-BNP. (Level of Evidence: B)

ESC Guidelines for blood tests for routine reassessment in patients with chronic stable angina (DO NOT EDIT)[2]

Class IIa

1. Fasting lipid profile and fasting glucose on an annual basis. (Level of Evidence: C)

Vote on and Suggest Revisions to the Current Guidelines

Sources

  • Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology [2]
  • The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina [1]
  • TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina [3]
  • The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina [4]

References

  1. 1.0 1.1 Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina). Circulation 99 (21):2829-48. PMID: 10351980
  2. 2.0 2.1 2.2 Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F; et al. (2006). "Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology". Eur Heart J. 27 (11): 1341–81. doi:10.1093/eurheartj/ehl001. PMID 16735367.
  3. Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). Circulation 107 (1):149-58. PMID: 12515758
  4. Fraker TD, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J et al. (2007) 2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina. Circulation 116 (23):2762-72. DOI:10.1161/CIRCULATIONAHA.107.187930 PMID: 17998462


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