Chondrosarcoma medical therapy: Difference between revisions
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{{Chondrosarcoma}} | {{Chondrosarcoma}} | ||
{{CMG}} | {{CMG}};{{AE}} {{Rohan}} | ||
==Overview== | ==Overview== | ||
[[Chemotherapy]] and [[radiotherapy]] are indicated for chondrosarcoma as [[adjuvant therapy]]. | [[Chemotherapy]] and [[radiotherapy]] are indicated for chondrosarcoma as [[adjuvant therapy]] or [[Palliative care|palliative]] treatment in surgically inaccessible areas. [[Surgery]] is the mainstay of treatment for chondrosarcoma. | ||
==Medical Therapy== | ==Medical Therapy== | ||
*[[Chemotherapy]] or traditional [[radiotherapy]] are not very effective for most chondrosarcomas. | *[[Chemotherapy]] or traditional [[radiotherapy]] are not very effective for most chondrosarcomas.<ref name="pmid17720491">{{cite journal| author=Grimer RJ, Gosheger G, Taminiau A, Biau D, Matejovsky Z, Kollender Y et al.| title=Dedifferentiated chondrosarcoma: prognostic factors and outcome from a European group. | journal=Eur J Cancer | year= 2007 | volume= 43 | issue= 14 | pages= 2060-5 | pmid=17720491 | doi=10.1016/j.ejca.2007.06.016 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17720491 }} </ref><ref name="pmid30559960">{{cite journal| author=Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ| title=Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment. | journal=Clin Sarcoma Res | year= 2018 | volume= 8 | issue= | pages= 23 | pmid=30559960 | doi=10.1186/s13569-018-0110-1 | pmc=6293503 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30559960 }} </ref><ref>{{cite book | last = Peabody | first = Terrance | title = Orthopaedic oncology : primary and metastatic tumors of the skeletal system | publisher = Springer | location = Cham | year = 2014 | isbn = 9783319073224 }}</ref><ref>{{cite book | last = Czerniak | first = Bogdan | title = Dorfman and Czerniak's bone tumors | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2016 | isbn = 9780323023962 }}</ref> | ||
*Wide spread [[metastasis]] is usually an indication for systemic [[Radiation therapy|radiotherapy]] or [[chemotherapy]]. | |||
* | *It is also indicated as a [[palliative treatment]] in surgically inaccessible areas. | ||
*[[Surgery]] is the mainstay of treatment for chondrosarcoma. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
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Latest revision as of 20:07, 24 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]
Overview
Chemotherapy and radiotherapy are indicated for chondrosarcoma as adjuvant therapy or palliative treatment in surgically inaccessible areas. Surgery is the mainstay of treatment for chondrosarcoma.
Medical Therapy
- Chemotherapy or traditional radiotherapy are not very effective for most chondrosarcomas.[1][2][3][4]
- Wide spread metastasis is usually an indication for systemic radiotherapy or chemotherapy.
- It is also indicated as a palliative treatment in surgically inaccessible areas.
- Surgery is the mainstay of treatment for chondrosarcoma.
References
- ↑ Grimer RJ, Gosheger G, Taminiau A, Biau D, Matejovsky Z, Kollender Y; et al. (2007). "Dedifferentiated chondrosarcoma: prognostic factors and outcome from a European group". Eur J Cancer. 43 (14): 2060–5. doi:10.1016/j.ejca.2007.06.016. PMID 17720491.
- ↑ Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
- ↑ Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
- ↑ Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.