Chondrosarcoma surgery

Jump to navigation Jump to search

Chondrosarcoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Chondrosarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Chondrosarcoma surgery On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chondrosarcoma surgery

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Chondrosarcoma surgery

CDC on Chondrosarcoma surgery

Chondrosarcoma surgery in the news

Blogs on Chondrosarcoma surgery

Directions to Hospitals Treating Chondrosarcoma

Risk calculators and risk factors for Chondrosarcoma surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rohan A. Bhimani, M.B.B.S., D.N.B., M.Ch.[2]

Overview

Surgery is the mainstay of treatment for chondrosarcoma. Adjunctive chemotherapy and radiation may be required. Recurrence rate depends on the grade of chondrosarcoma.

Surgery

Intra-Lesional Curettage

Indications

Wide Surgical Excision

Indications

  • Grade 2 or 3 chondrosarcoma anywhere in the body.
  • Grade 1 chondrosarcoma in pelvis.

Wide Surgical Excision Combined with Multi-Agent Chemotherapy

Indications

  • Mesenchymal chondrosarcoma.

Limb-salvage through Pelvic Resection with or without Reconstruction

Indications

  • Dedifferentiated chondrosarcoma involving the pelvis.[6]

Limb-sacrifice with Hindquarter Amputation

Indications

  • Dedifferentiated chondrosarcoma involving the pelvis[6]

Recurrence Rate

Grade 1 chondrosarcoma

Grade 2 chondrosarcoma

  • The recurrence rate varies depending on resection margins.

Grade 3 chondrosarcoma

  • The local recurrence rate is 25% and >30% chances of metastasis.
Chondrosarcoma of glenoid and scapula. Source: Case courtesy by: Dr. Rohan A. Bhimani


References

  1. Peabody, Terrance (2014). Orthopaedic oncology : primary and metastatic tumors of the skeletal system. Cham: Springer. ISBN 9783319073224.
  2. Czerniak, Bogdan (2016). Dorfman and Czerniak's bone tumors. Philadelphia, PA: Elsevier/Saunders. ISBN 9780323023962.
  3. Lex JR, Evans S, Stevenson JD, Parry M, Jeys LM, Grimer RJ (2018). "Dedifferentiated chondrosarcoma of the pelvis: clinical outcomes and current treatment". Clin Sarcoma Res. 8: 23. doi:10.1186/s13569-018-0110-1. PMC 6293503. PMID 30559960.
  4. Ozaki T, Lindner N, Hillmann A, Rödl R, Blasius S, Winkelmann W (1996). "Influence of intralesional surgery on treatment outcome of chondrosarcoma". Cancer. 77 (7): 1292–7. doi:10.1002/(SICI)1097-0142(19960401)77:7<1292::AID-CNCR10>3.0.CO;2-X. PMID 8608505.
  5. Marco RA, Gitelis S, Brebach GT, Healey JH (2000). "Cartilage tumors: evaluation and treatment". J Am Acad Orthop Surg. 8 (5): 292–304. PMID 11029557.
  6. 6.0 6.1 Dickey ID, Rose PS, Fuchs B, Wold LE, Okuno SH, Sim FH; et al. (2004). "Dedifferentiated chondrosarcoma: the role of chemotherapy with updated outcomes". J Bone Joint Surg Am. 86-A (11): 2412–8. PMID 15523011.


Template:WikiDoc Sources